Plant Actin Related Protein 2/3 Complex Subunit 2 (ARPC2) ELISA Kit | ARPC2 elisa kit
Plant Actin Related Protein 2/3 Complex Subunit 2 (ARPC2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family.
Protein type: Cytoskeletal; Actin-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q36.1
Cellular Component: actin cytoskeleton; Arp2/3 protein complex; cytoplasm; cytosol; focal adhesion; Golgi apparatus
Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton
Biological Process: cell motility; ephrin receptor signaling pathway