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Polymeric immunoglobulin receptor (Pigr) Recombinant Protein | Pigr recombinant protein

Recombinant Rat Polymeric immunoglobulin receptor (Pigr)

Gene Names
Pigr; pIgA-R; RNPIGR2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Polymeric immunoglobulin receptor (Pigr); Recombinant Rat Polymeric immunoglobulin receptor (Pigr); Polymeric immunoglobulin receptor; PIgR; Poly-Ig receptorCleaved into the following chain:; 1. Secretory component; Pigr recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
19-643
Sequence
QS PIFGPQDVSS IEGNSVSITC YYPDTSVNRH TRKYWCRQGA NGYCATLISS NGYLSKEYSG RASLINFPEN STFVINIAHL TQEDTGSYKC GLGTTNRGLF FDVSLEVSQV PEFPNDTHVY TKDIGRTVTI ECRFKEGNAH SKKSLCKKRG EACEVVIDST EYVDPSYKDR AILFMKGTSR DIFYVNISHL IPSDAGLYVC QAGEGPSADK NNADLQVLEP EPELLYKDLR SSVTFECDLG REVANDAKYL CRKNKETCDV IINTLGKRDP AFEGRILLTP RDDNGRFSVL ITGLRKEDAG HYQCGAHSSG LPQEGWPVQA WQLFVNEEST IPNSRSVVKG VTGGSVAIVC PYNPKESSSL KYWCHWEADE NGRCPVLVGT QALVQEGYEG RLALFDQPGS GAYTVILNQL TTQDSGFYWC LTDGDSRWRT TIELQVAEAT KKPDLEVTPQ NATAVIGETF TISCHYPCKF YSQEKYWCKW SNDGCHILPS HDEGARQSSV SCDQSSQIVS MTLNPVKKED EGWYWCGVKE GQVYGETTAI YVAVEERTRG SPHINPTDAN ARAKDAPEEE AMESSVREDE NKANLDPRLF ADEREIQNAG DQAQENRASG NAGSAGGQSG SSK
Sequence Length
625
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84,798 Da
NCBI Official Full Name
polymeric immunoglobulin receptor
NCBI Official Synonym Full Names
polymeric immunoglobulin receptor
NCBI Official Symbol
Pigr
NCBI Official Synonym Symbols
pIgA-R; RNPIGR2
NCBI Protein Information
polymeric immunoglobulin receptor; poly-Ig receptor; polymeric IgA receptor
UniProt Protein Name
Polymeric immunoglobulin receptor
UniProt Gene Name
Pigr
UniProt Synonym Gene Names
PIgR; Poly-Ig receptor
UniProt Entry Name
PIGR_RAT

NCBI Description

contains a trinucleotide repeat-rich fragment in the 3' untranslated region that may regulate gene expression [RGD, Feb 2006]

Uniprot Description

PIGR: This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Protein type: Receptor, misc.; Membrane protein, integral; Immunoglobulin superfamily

Cellular Component: extracellular space; transport vesicle; recycling endosome membrane; integral to membrane; extracellular region; plasma membrane; receptor complex

Molecular Function: polymeric immunoglobulin receptor activity; epidermal growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; retinal homeostasis; detection of chemical stimulus involved in sensory perception of bitter taste; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; receptor clustering

Research Articles on Pigr

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Product Notes

The Pigr pigr (Catalog #AAA1118025) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-643. The amino acid sequence is listed below: QS PIFGPQDVSS IEGNSVSITC YYPDTSVNRH TRKYWCRQGA NGYCATLISS NGYLSKEYSG RASLINFPEN STFVINIAHL TQEDTGSYKC GLGTTNRGLF FDVSLEVSQV PEFPNDTHVY TKDIGRTVTI ECRFKEGNAH SKKSLCKKRG EACEVVIDST EYVDPSYKDR AILFMKGTSR DIFYVNISHL IPSDAGLYVC QAGEGPSADK NNADLQVLEP EPELLYKDLR SSVTFECDLG REVANDAKYL CRKNKETCDV IINTLGKRDP AFEGRILLTP RDDNGRFSVL ITGLRKEDAG HYQCGAHSSG LPQEGWPVQA WQLFVNEEST IPNSRSVVKG VTGGSVAIVC PYNPKESSSL KYWCHWEADE NGRCPVLVGT QALVQEGYEG RLALFDQPGS GAYTVILNQL TTQDSGFYWC LTDGDSRWRT TIELQVAEAT KKPDLEVTPQ NATAVIGETF TISCHYPCKF YSQEKYWCKW SNDGCHILPS HDEGARQSSV SCDQSSQIVS MTLNPVKKED EGWYWCGVKE GQVYGETTAI YVAVEERTRG SPHINPTDAN ARAKDAPEEE AMESSVREDE NKANLDPRLF ADEREIQNAG DQAQENRASG NAGSAGGQSG SSK. It is sometimes possible for the material contained within the vial of "Polymeric immunoglobulin receptor (Pigr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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