Rat Platelet factor 4 ELISA Kit | Pf4 elisa kit
Rat Platelet factor 4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
member of low-molecular weight chemokines superfamily; may mediate inflammation and immune response [RGD, Feb 2006]
Uniprot Description
PF4: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Chemokine; Apoptosis; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Cellular Component: extracellular space; protein complex; vesicle
Molecular Function: chemokine activity; CXCR chemokine receptor binding; CXCR3 chemokine receptor binding; heparin binding
Biological Process: cytokine and chemokine mediated signaling pathway; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; leukocyte chemotaxis; negative regulation of angiogenesis; negative regulation of cytolysis; negative regulation of megakaryocyte differentiation; negative regulation of MHC class II biosynthetic process; platelet activation; positive regulation of cAMP metabolic process; positive regulation of leukocyte chemotaxis; positive regulation of macrophage differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; protein complex assembly; regulation of cell proliferation; response to lipopolysaccharide
Research Articles on Pf4
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Product Notes
The Rat Pf4 pf4 (Catalog #AAA2880161) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880161 ELISA Kit recognizes Rat Pf4. It is sometimes possible for the material contained within the vial of "Platelet factor 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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