Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Lane 1: Recombinant Human CXCL4 Protein 10ng; Lane 2: Recombinant Human CXCL4 Protein 5ng; Lane 3: Recombinant Human CXCL4 Protein 2.5ng)

Rabbit CXCL4 Polyclonal Antibody | anti-CXCL4 antibody

CXCL4 antibody

Gene Names
Pf4; PF-4; Pf4a; Cxcl4; RATPF4A
Applications
Western Blot, Immunohistochemistry
Purity
CXCL4 antibody was purified by affinity chromatography
Synonyms
CXCL4; Polyclonal Antibody; CXCL4 antibody; Polyclonal CXCL4; Anti-CXCL4; Platelet Factor-4; Oncostatin A; CXCL 4; PF-4; PF4; CXCL-4; Ironplact; anti-CXCL4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
CXCL4 antibody was purified by affinity chromatography
Form/Format
Supplied in lyophilized form
Sequence Length
21
Applicable Applications for anti-CXCL4 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
CXCL4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis.
Immunogen
CXCL4 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human CXCL4 as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C, avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Lane 1: Recombinant Human CXCL4 Protein 10ng; Lane 2: Recombinant Human CXCL4 Protein 5ng; Lane 3: Recombinant Human CXCL4 Protein 2.5ng)

Western Blot (WB) (Lane 1: Recombinant Human CXCL4 Protein 10ng; Lane 2: Recombinant Human CXCL4 Protein 5ng; Lane 3: Recombinant Human CXCL4 Protein 2.5ng)
Related Product Information for anti-CXCL4 antibody
Affinity purified Rabbit polyclonal CXCL4 antibody
Product Categories/Family for anti-CXCL4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
11,287 Da
NCBI Official Full Name
chemokine (C-X-C motif) ligand 4, isoform CRA_c
NCBI Official Synonym Full Names
platelet factor 4
NCBI Official Symbol
Pf4
NCBI Official Synonym Symbols
PF-4; Pf4a; Cxcl4; RATPF4A
NCBI Protein Information
platelet factor 4
UniProt Protein Name
Platelet factor 4
UniProt Gene Name
Pf4
UniProt Synonym Gene Names
Cxcl4; Scyb4; PF-4
UniProt Entry Name
PLF4_RAT

NCBI Description

member of low-molecular weight chemokines superfamily; may mediate inflammation and immune response [RGD, Feb 2006]

Uniprot Description

PF4: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Chemokine; Secreted, signal peptide; Apoptosis; Secreted

Cellular Component: extracellular space; protein complex; vesicle

Molecular Function: heparin binding; CXCR3 chemokine receptor binding; chemokine activity; CXCR chemokine receptor binding

Biological Process: negative regulation of cytolysis; platelet activation; cytokine and chemokine mediated signaling pathway; leukocyte chemotaxis; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; positive regulation of tumor necrosis factor production; negative regulation of megakaryocyte differentiation; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; negative regulation of MHC class II biosynthetic process; protein complex assembly; positive regulation of transcription from RNA polymerase II promoter; immune response; inflammatory response; positive regulation of macrophage differentiation

Research Articles on CXCL4

Similar Products

Product Notes

The CXCL4 pf4 (Catalog #AAA839716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CXCL4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the CXCL4 pf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXCL4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.