Human pellino homolog 2 (Drosophila) ELISA Kit | PELI2 elisa kit
Human Protein pellino homolog 2, PELI2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PELI2: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation. Belongs to the pellino family.
Protein type: Ubiquitin conjugating system; Adaptor/scaffold; Ubiquitin ligase; EC 6.3.2.19; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 14q21
Cellular Component: cytosol
Molecular Function: protein binding; ligase activity
Biological Process: toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAPKKK cascade; toll-like receptor signaling pathway; innate immune response; protein ubiquitination; positive regulation of protein amino acid phosphorylation; toll-like receptor 9 signaling pathway; toll-like receptor 4 signaling pathway; Toll signaling pathway; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway
Research Articles on PELI2
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Product Notes
The Human PELI2 peli2 (Catalog #AAA9340417) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340417 ELISA Kit recognizes Human PELI2. It is sometimes possible for the material contained within the vial of "pellino homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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