Probable cation-transporting ATPase (At5g23630) Recombinant Protein | At5g23630 recombinant protein
Recombinant Arabidopsis thaliana Probable cation-transporting ATPase (At5g23630) , partial
NCBI and Uniprot Product Information
NCBI Description
A member of the eukaryotic type V subfamily (P5) of P-type ATPase cation pumps; MIA is most similar to the human P5 ATPase ATY2(44% identity) and to Spf1p from S. cerevisiae (41% identity). Highly abundant in the endoplasmic reticulum and small vesicles of developing pollen grains and tapetum cells. T-DNA insertional mutants of MIA suffer from imbalances in cation homeostasis and exhibit a severe reduction in fertility. Mutant microspores fail to separate from tetrads and pollen grains are fragile with an abnormal morphology and altered cell wall structure. MIA is also named PDR2 and was shown to be required for proper expression of SCARECROW (SCR), a key regulator of root patterning, and for stem-cell maintenance in Pi-deprived roots.
Uniprot Description
Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis (). Plays an important role in pollen and root development through its impact on protein secretion and transport processes. Functions together with LPR1 and LPR2 in a common pathway that adjusts root meristem activity to phosphate availability. Under phosphate limitation, restricts SHR movement in root meristem and is required for maintaining SCR expression in the root meristem stem-cell niche as well as for proximal meristem activity. Can complement the yeast spf1 mutant.
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Product Notes
The At5g23630 pdr2 (Catalog #AAA7101883) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Probable cation-transporting ATPase (At5g23630), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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