Human phosducin ELISA Kit | PDC elisa kit

Human Phosducin, PDC ELISA Kit

Cat. Num. AAA9316893

• Gene Names: PDC; PHD; MEKA; PhLP; PhLOP
• Reactivity: Human
• Synonyms: phosducin; Human Phosducin; PDC ELISA Kit; Human Phosducin (PDC) ELISA kit; MEKA; PHD; PhLOP; PhLP; 33kDA phototransducing protein; G beta gamma binding protein; phosducin-like orphan protein; PDC elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Serum, Plasma and Tissue Homogenate
• Assay Type: Sandwich
• Detection Range: 3.12ng/ml-100ng/ml.
• Sensitivity: 1.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for PDC elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of PDC (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 32967591
• NCBI GeneID: 5132
• NCBI Accession #: NP_002588.3
• NCBI GenBank Nucleotide #: NM_002597.4
• UniProt Accession #: P20941; Q14816; Q9UP22; Q9UP23
• Molecular Weight: 28,246 Da
• NCBI Official Full Name: phosducin isoform a
• NCBI Official Synonym Full Names: phosducin
• NCBI Official Symbol: PDC
• NCBI Official Synonym Symbols: PHD; MEKA; PhLP; PhLOP
• NCBI Protein Information: phosducin; G beta gamma binding protein; phosducin-like orphan protein; 33 kDa phototransducing protein
• UniProt Protein Name: Phosducin
• Protein Family: Phosducin
• UniProt Gene Name: PDC
• UniProt Synonym Gene Names: PHD
• UniProt Entry Name: PHOS_HUMAN

NCBI Description

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

phosducin: May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. Belongs to the phosducin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: photoreceptor outer segment; photoreceptor inner segment; cytosol; nucleus

Molecular Function: phospholipase inhibitor activity

Biological Process: G-protein coupled receptor protein signaling pathway; visual perception; negative regulation of catalytic activity; phototransduction