Human protocadherin gamma subfamily B, 7 ELISA Kit | PCDHGB7 elisa kit
Human Protocadherin gamma-B7, PCDHGB7 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Uniprot Description
PCDHGB7: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: plasma membrane; integral to membrane
Molecular Function: calcium ion binding
Biological Process: homophilic cell adhesion
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Product Notes
The Human PCDHGB7 pcdhgb7 (Catalog #AAA9321672) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321672 ELISA Kit recognizes Human PCDHGB7. It is sometimes possible for the material contained within the vial of "protocadherin gamma subfamily B, 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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