Ubiquitin Thioesterase OTUB2/OTUB2 Recombinant Protein | OTUB2 recombinant protein

Recombinant Human Ubiquitin Thioesterase OTUB2/OTUB2 Protein (N-GST)

Cat. Num. AAA2553343

• Gene Names: OTUB2; OTB2; OTU2; C14orf137
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Ubiquitin Thioesterase OTUB2/OTUB2; Recombinant Human Ubiquitin Thioesterase OTUB2/OTUB2 Protein (N-GST); Ubiquitin Thioesterase OTUB2; Deubiquitinating Enzyme OTUB2; OTU Comain-Containing Ubiquitin Aldehyde-Binding Protein 2; Otubain-2; Ubiquitin-Specific-Processing Protease OTUB2; OTUB2; C14orf137; OTB2; OTU2; OTUB2 recombinant protein

• Host: E Coli
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Supplied as a 0.2 mum filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, pH 7.5.
• Sequence Positions: Met1-His234
• Sequence Length: 234

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fusion Tag: N-GST
• Preparation and Storage: Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Related Product Information for OTUB2 recombinant protein

Ubiquitin Thioesterase OTUB2 belongs to the peptidase C65 family, functions as a hydrolase that can remove conjugated ubiquitin from proteins in vitro, may plays an important regulatory role at the level of protein turnover by preventing degradation. OTUB2 is expressed at higher levels in the brain.

NCBI and Uniprot Product Information

• NCBI GI #: 12962939
• NCBI GeneID: 78990
• NCBI Accession #: NP_075601.1
• NCBI GenBank Nucleotide #: NM_023112.3
• UniProt Accession #: Q96DC9; Q6IA10; Q9H6T1
• Molecular Weight: Molecular Mass: 53.6 kDa; Actual Protein Molecular Mass: 52 kDa
• NCBI Official Full Name: ubiquitin thioesterase OTUB2
• NCBI Official Synonym Full Names: OTU deubiquitinase, ubiquitin aldehyde binding 2
• NCBI Official Symbol: OTUB2
• NCBI Official Synonym Symbols: OTB2; OTU2; C14orf137
• NCBI Protein Information: ubiquitin thioesterase OTUB2
• UniProt Protein Name: Ubiquitin thioesterase OTUB2
• Protein Family: Ubiquitin thioesterase
• UniProt Gene Name: OTUB2
• UniProt Synonym Gene Names: C14orf137; OTB2; OTU2

NCBI Description

This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011]

Uniprot Description

Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.