Mouse anti-Human GATAD1 Monoclonal Antibody | anti-GATAD1 antibody

GATAD1 (GATA Zinc Finger Domain Containing 1, GATAD1 Protein, FLJ22489, FLJ40695, Ocular Development-associated Gene, ODAG, RG083M05.2, tcag7.279)

Cat. Num. AAA608898

• Gene Names: GATAD1; ODAG; FLJ22489; FLJ40695; RG083M05.2
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: GATAD1; Monoclonal Antibody; GATAD1 (GATA Zinc Finger Domain Containing 1; GATAD1 Protein; FLJ22489; FLJ40695; Ocular Development-associated Gene; ODAG; RG083M05.2; tcag7.279); Anti -GATAD1 (GATA Zinc Finger Domain Containing 1; anti-GATAD1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 9j50
• Specificity: Recognizes human GATAD1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.4, 1% BSA and 0.05% sodium azide.

• Applicable Applications for anti-GATAD1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Synthetic peptide corresponding to the N-terminal region of human GATAD1
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-GATAD1 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 88759346
• NCBI GeneID: 57798
• NCBI Accession #: NP_066990.3
• NCBI GenBank Nucleotide #: NM_021167.3
• UniProt Accession #: Q8WUU5; Q8N5Y5; Q99995; Q9H689; B2RE37; D6W5Q5
• Molecular Weight: 28,690 Da
• NCBI Official Full Name: GATA zinc finger domain-containing protein 1
• NCBI Official Synonym Full Names: GATA zinc finger domain containing 1
• NCBI Official Symbol: GATAD1
• NCBI Official Synonym Symbols: ODAG; FLJ22489; FLJ40695; RG083M05.2
• NCBI Protein Information: GATA zinc finger domain-containing protein 1; OTTHUMP00000161848; ocular development associated; ocular development-associated gene protein
• UniProt Protein Name: GATA zinc finger domain-containing protein 1
• Protein Family: GATA zinc finger domain-containing protein
• UniProt Gene Name: GATAD1
• UniProt Synonym Gene Names: ODAG
• UniProt Entry Name: GATD1_HUMAN

NCBI Description

The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Uniprot Description

GATAD1: Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me). Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B). CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: nucleoplasm; nucleus

Molecular Function: zinc ion binding; sequence-specific DNA binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent

Disease: Cardiomyopathy, Dilated, 2b