SDS-PAGE
OMGP / OMG recombinant protein
Recombinant Mouse OMGP / OMG Protein (aa 1-245, His tag)
Purity
> 95 % as determined by SDS-PAGE
Synonyms
OMGP / OMG; Recombinant Mouse OMGP / OMG Protein (aa 1-245; His tag); RP23-67E18.6; LNGFR; Tnfrsf16; p75; p75NGFR; p75NTR; OMGP / OMG recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
443
Application Notes
The secreted recombinant mouse OMGP (aa 1-245) comprises 232 amino acids and has a calculated molecular mass of 27 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Ile 25
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for OMGP / OMG recombinant protein
Background: Mouse oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein which contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.
Description: A DNA sequence encoding the amino acids (Met 1-Thr 245) of mouse OMGP (Q63912) was expressed, with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the amino acids (Met 1-Thr 245) of mouse OMGP (Q63912) was expressed, with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,284 Da
NCBI Official Full Name
oligodendrocyte-myelin glycoprotein
NCBI Official Synonym Full Names
oligodendrocyte myelin glycoprotein
NCBI Official Symbol
Omg
NCBI Protein Information
oligodendrocyte-myelin glycoprotein
UniProt Protein Name
Oligodendrocyte-myelin glycoprotein
UniProt Gene Name
Omg
UniProt Synonym Gene Names
Omgp
Uniprot Description
OMG: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 11 B5|11 46.79 cM
Cellular Component: myelin sheath; plasma membrane
Molecular Function: identical protein binding; protein homodimerization activity
Biological Process: myelination in the central nervous system; neurite regeneration; regulation of collateral sprouting of intact axon in response to injury
Research Articles on OMGP / OMG
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Product Notes
The OMGP / OMG omg (Catalog #AAA2546851) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse OMGP (aa 1-245) comprises 232 amino acids and has a calculated molecular mass of 27 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 44 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the OMGP / OMG omg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OMGP / OMG, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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