SDS-Page
OMGP Recombinant Protein | OMG recombinant protein
OMGP Protein, Human, Recombinant (aa 1-420, His Tag)
Gene Names
OMG; OMGP
Purity
>97% as determined by SDS-PAGE
Synonyms
OMGP; OMGP Protein; Human; Recombinant (aa 1-420; His Tag); Human OMGP/OMG Protein (aa 1-420; oligodendrocyte myelin glycoprotein; OMG recombinant protein
Host
HEK293 Cells
Purity/Purification
>97% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Asn420
Species
Human
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Ile 25
Tag
C-His
Protein Construction
A DNA sequence encoding the mature form of human OMGP (P23515-1)(Met 1-Asn 420) without the pro peptide was expressed, fused with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for OMG recombinant protein
Background: Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG/OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG/OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG/OMGP play roles in both the developing and adult central nervous system. OMG/OMGP participates in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG/OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG/OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting, and myelination are crucial processes involved in brain development and regeneration after injury.
References
Viskochil D., et al.,(1991), The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene. Mol. Cell. Biol. 11:906-912.Mikol D.D., et al., (1990), The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate.J. Cell Biol. 110:471-479.Mikol D.D., et al.,(1990), Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein.J. Cell Biol. 111:2673-2679.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,608 Da
NCBI Official Full Name
oligodendrocyte-myelin glycoprotein
NCBI Official Synonym Full Names
oligodendrocyte myelin glycoprotein
NCBI Official Symbol
OMG
NCBI Official Synonym Symbols
OMGP
NCBI Protein Information
oligodendrocyte-myelin glycoprotein
UniProt Protein Name
Oligodendrocyte-myelin glycoprotein
Protein Family
UniProt Gene Name
OMG
UniProt Synonym Gene Names
OMGP
UniProt Entry Name
OMGP_HUMAN
Uniprot Description
OMG: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: plasma membrane
Molecular Function: identical protein binding
Biological Process: nerve growth factor receptor signaling pathway; neurite regeneration; negative regulation of axonogenesis; cell adhesion; regulation of axonogenesis; regulation of collateral sprouting of intact axon in response to injury
Research Articles on OMG
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Product Notes
The OMG omg (Catalog #AAA8120151) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Asn42 0. It is sometimes possible for the material contained within the vial of "OMGP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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