Human nuclear RNA export factor 5 ELISA Kit | NXF5 elisa kit

Human Nuclear RNA export factor 5, NXF5 ELISA Kit

Cat. Num. AAA9341557

• Reactivity: Human
• Synonyms: nuclear RNA export factor 5; Human Nuclear RNA export factor 5; NXF5 ELISA Kit; Human Nuclear RNA export factor 5 (NXF5) ELISA kit; NXF5 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 254039592
• NCBI GeneID: 55998
• NCBI Accession #: NP_116564.2
• NCBI GenBank Nucleotide #: NM_032946.2
• UniProt Accession #: Q9H1B4; Q9H1B0; Q9H1B1; Q9H1B2; Q9H1B3; A2RRM0; B1AV82; B1AV83; B1AV84; B1AV85
• Molecular Weight: 45,628 Da
• NCBI Official Full Name: nuclear RNA export factor 5
• NCBI Official Synonym Full Names: nuclear RNA export factor 5
• NCBI Official Symbol: NXF5
• NCBI Protein Information: nuclear RNA export factor 5; TAPL-1; TAP-like protein 1
• UniProt Protein Name: Nuclear RNA export factor 5
• Protein Family: Nuclear RNA export factor
• UniProt Gene Name: NXF5
• UniProt Synonym Gene Names: TAPL1; TAPL-1
• UniProt Entry Name: NXF5_HUMAN

NCBI Description

This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009]

Uniprot Description

NXF5: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons. A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5. Belongs to the NXF family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; RNA binding; nucleotide binding

Biological Process: mRNA export from nucleus; multicellular organismal development; RNA transport