Western Blot (WB)
(NXF5 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the NXF5 Antibody detected the NXF5 protein (arrow).)
Rabbit anti-Human NXF5 Polyclonal Antibody | anti-NXF5 antibody
NXF5 Antibody (N-term)
Western Blot (WB)
(NXF5 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the NXF5 Antibody detected the NXF5 protein (arrow).)
Western Blot (WB)
(NXF5 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the NXF5 Antibody detected the NXF5 protein (arrow).)
factor genes. The encoded protein can bind RNA, and is implicated
in mRNA nuclear export. However, this protein has lost several
C-terminal protein domains found in other family members that are
required for export activity, and may be an evolving pseudogene.
Alternatively spliced transcript variants have been described, but
most are candidates for nonsense-mediated decay (NMD) and may not
express proteins in vivo.
Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
Frints, S.G., et al. Am. J. Med. Genet. A 119A (3), 367-374 (2003) :
Jun, L., et al. Curr. Biol. 11(18):1381-1391(2001)
Herold, A., et al. Mol. Cell. Biol. 20(23):8996-9008(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009]
Uniprot Description
NXF5: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons. A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5. Belongs to the NXF family. 6 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: Xq22
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; RNA binding; nucleotide binding
Biological Process: mRNA export from nucleus; multicellular organismal development; RNA transport
Research Articles on NXF5
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Product Notes
The NXF5 nxf5 (Catalog #AAA9210499) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 53-80. The NXF5 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NXF5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NXF5 nxf5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NXF5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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