BDNF/NT-3 growth factors receptor Recombinant Protein | Ntrk2 recombinant protein
BDNF/NT-3 growth factors receptor
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
TrkB: a receptor tyrosine kinase of the Trk family. Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3, -4 and -5 but not nerve growth factor (NGF). Involved in the development and maintenance of the nervous system. Three splice variant isoforms have been described.
Protein type: Membrane protein, integral; Protein kinase, TK; Kinase, protein; EC 2.7.10.1; Protein kinase, tyrosine (receptor); TK group; Trk family
Cellular Component: axon; cell soma; cell surface; cytoplasm; cytosol; dendrite; dendritic spine; endosome; excitatory synapse; growth cone; integral to plasma membrane; nerve terminal; perikaryon; plasma membrane; postsynaptic density; postsynaptic membrane; presynaptic active zone; receptor complex; rough endoplasmic reticulum; terminal button
Molecular Function: brain-derived neurotrophic factor binding; brain-derived neurotrophic factor receptor activity; neurotrophin binding; neurotrophin receptor activity; protein binding; protein homodimerization activity; receptor tyrosine kinase binding; transmembrane receptor protein tyrosine kinase activity
Biological Process: brain-derived neurotrophic factor receptor signaling pathway; central nervous system neuron development; cerebral cortex development; feeding behavior; glutamate secretion; learning; long-term memory; mechanoreceptor differentiation; negative regulation of neuron apoptosis; neuromuscular junction development; neuron differentiation; neuron migration; oligodendrocyte differentiation; peripheral nervous system neuron development; positive regulation of axonogenesis; positive regulation of cell proliferation; positive regulation of MAPKKK cascade; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of synaptic transmission, glutamatergic; positive regulation of synaptogenesis; protein amino acid autophosphorylation; regulation of dendrite development; regulation of GTPase activity; regulation of MAPKKK cascade; regulation of metabolic process; regulation of neurotransmitter secretion; regulation of protein kinase B signaling cascade; retina development in camera-type eye; retinal rod cell development; vasculogenesis
Research Articles on Ntrk2
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Product Notes
The Ntrk2 ntrk2 (Catalog #AAA7043168) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 32-821aa; full length protein. The amino acid sequence is listed below: CPTSCKCSSA RIWCTEPSPG IVAFPRLEPN SVDPENITEI LIANQKRLEI INEDDVEAYV GLRNLTIVDS GLKFVAYKAF LKNSNLRHIN FTRNKLTSLS RRHFRHLDLS DLILTGNPFT CSCDIMWLKT LQETKSSPDT QDLYCLNESS KNMPLANLQI PNCGLPSARL AAPNLTVEEG KSVTLSCSVG GDPLPTLYWD VGNLVSKHMN ETSHTQGSLR ITNISSDDSG KQISCVAENL VGEDQDSVNL TVHFAPTITF LESPTSDHHW CIPFTVRGNP KPALQWFYNG AILNESKYIC TKIHVTNHTE YHGCLQLDNP THMNNGDYTL MAKNEYGKDE RQISAHFMGR PGVDYETNPN YPEVLYEDWT TPTDIGDTTN KSNEIPSTDV ADQSNREHLS VYAVVVIASV VGFCLLVMLL LLKLARHSKF GMKGPASVIS NDDDSASPLH HISNGSNTPS SSEGGPDAVI IGMTKIPVIE NPQYFGITNS QLKPDTFVQH IKRHNIVLKR ELGEGAFGKV FLAECYNLCP EQDKILVAVK TLKDASDNAR KDFHREAELL TNLQHEHIVK FYGVCVEGDP LIMVFEYMKH GDLNKFLRAH GPDAVLMAEG NPPTELTQSQ MLHIAQQIAA GMVYLASQHF VHRDLATRNC LVGENLLVKI GDFGMSRDVY STDYYRVGGH TMLPIRWMPP ESIMYRKFTT ESDVWSLGVV LWEIFTYGKQ PWYQLSNNEV IECITQGRVL QRPRTCPQEV YELMLGCWQR EPHTRKNIKS IHTLLQNLAK ASPVYLDILG. It is sometimes possible for the material contained within the vial of "BDNF/NT-3 growth factors receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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