LRRC33 Blocking Peptide | NRROS blocking peptide
LRRC33 Antibody (C-term) Blocking peptide
Gene Names
NRROS; GARPL1; LRRC33; UNQ3030; ELLP3030
Synonyms
LRRC33; LRRC33 Antibody (C-term) Blocking peptide; Negative regulator of reactive oxygen species; Leucine-rich repeat-containing protein 33; NRROS; NRROS blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
692
Cellular Location
Cell membrane; Single-pass type I membrane protein Endoplasmic reticulum membrane; Single-pass type I membrane protein
Tissue Location
Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NRROS blocking peptide
Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex (By similarity). May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,366 Da
NCBI Official Full Name
negative regulator of reactive oxygen species
NCBI Official Synonym Full Names
negative regulator of reactive oxygen species
NCBI Official Symbol
NRROS
NCBI Official Synonym Symbols
GARPL1; LRRC33; UNQ3030; ELLP3030
NCBI Protein Information
negative regulator of reactive oxygen species
UniProt Protein Name
Negative regulator of reactive oxygen species
Protein Family
UniProt Gene Name
NRROS
UniProt Synonym Gene Names
LRRC33
UniProt Entry Name
NRROS_HUMAN
Uniprot Description
NRROS: May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. Interacts (via LRR repeats) with TLR2, TLR3, TLR4, TLR9 and probably other Toll-like receptors
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: endoplasmic reticulum
Biological Process: immune response; inflammatory response; superoxide metabolic process
Research Articles on NRROS
Similar Products
Product Notes
The NRROS nrros (Catalog #AAA9217533) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LRRC33, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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