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Western Blot (WB) (LRRC33 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the LRRC33 antibody detected the LRRC33 protein (arrow).)

Rabbit anti-Human LRRC33 Polyclonal Antibody | anti-NRROS antibody

LRRC33 Antibody (C-term)

Gene Names
NRROS; GARPL1; LRRC33; UNQ3030; ELLP3030
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LRRC33; Polyclonal Antibody; LRRC33 Antibody (C-term); Negative regulator of reactive oxygen species; Leucine-rich repeat-containing protein 33; NRROS; anti-NRROS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LRRC33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-640 amino acids from the C-terminal region of human LRRC33.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
611-640
Sequence Length
692
Applicable Applications for anti-NRROS antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(LRRC33 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the LRRC33 antibody detected the LRRC33 protein (arrow).)

Western Blot (WB) (LRRC33 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the LRRC33 antibody detected the LRRC33 protein (arrow).)

Immunohistochemistry (IHC)

(LRRC33 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph node followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LRRC33 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (LRRC33 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph node followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LRRC33 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-NRROS antibody
References
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76366
NCBI Official Full Name
negative regulator of reactive oxygen species
NCBI Official Synonym Full Names
negative regulator of reactive oxygen species
NCBI Official Symbol
NRROS
NCBI Official Synonym Symbols
GARPL1; LRRC33; UNQ3030; ELLP3030
NCBI Protein Information
negative regulator of reactive oxygen species
UniProt Protein Name
Negative regulator of reactive oxygen species
UniProt Gene Name
NRROS
UniProt Synonym Gene Names
LRRC33
UniProt Entry Name
NRROS_HUMAN

Uniprot Description

NRROS: May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. Interacts (via LRR repeats) with TLR2, TLR3, TLR4, TLR9 and probably other Toll-like receptors

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; plasma membrane

Biological Process: superoxide metabolic process; innate immune response; immune response; inflammatory response

Research Articles on NRROS

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Product Notes

The NRROS nrros (Catalog #AAA9205511) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 611-640. The LRRC33 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC33 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the NRROS nrros for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC33, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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