Mouse nuclear receptor subfamily 1, group H, member 2 ELISA Kit | NR1H2 elisa kit
Mouse Oxysterols receptor LXR-beta, NR1H2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
LXR-beta: Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Forms a heterodimer with RXR. Ubiquitous. Belongs to the nuclear hormone receptor family. NR1 subfamily.
Protein type: Nuclear receptor
Cellular Component: cytoplasm; nucleus
Molecular Function: retinoid X receptor binding; ligand-dependent nuclear receptor activity; protein binding; DNA binding; zinc ion binding; sequence-specific DNA binding; metal ion binding; steroid hormone receptor activity; apolipoprotein A-I receptor binding; transcription factor activity; ATPase binding
Biological Process: transcription from RNA polymerase II promoter; negative regulation of proteolysis; negative regulation of lipid transport; retinoic acid receptor signaling pathway; positive regulation of fatty acid biosynthetic process; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of cellular protein metabolic process; lipid homeostasis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of pinocytosis; cellular lipid metabolic process; positive regulation of cholesterol transport; regulation of transcription from RNA polymerase II promoter; cholesterol homeostasis; regulation of transcription, DNA-dependent; positive regulation of lipoprotein lipase activity; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
Research Articles on NR1H2
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Product Notes
The Mouse NR1H2 nr1h2 (Catalog #AAA9319346) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319346 ELISA Kit recognizes Mouse NR1H2. It is sometimes possible for the material contained within the vial of "nuclear receptor subfamily 1, group H, member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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