Mouse NLR family, pyrin domain containing 5 ELISA Kit | NLRP5 elisa kit
Mouse NACHT, LRR and PYD domains-containing protein 5, NLRP5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the NACHT, leucine-rich repeat, and pyrin domain containing family. Members of this family have a pyrin domain at the N-terminus, a central NACHT domain, and a C-terminal leucine-rich repeat domain. This gene encodes a maternal-effect factor that is essential for early embryonic development in the mouse. Homozygous null mutant females are sterile, and embryos die following the first cleavage. This gene is required for endoplasmic reticulum redistribution and calcium homeostasis in oocytes. In addition, ovulated oocytes mutant for this gene have abnormal mitochondrial localization and increased mitochondrial activity, which results in mitochondrial damage and early embryonic lethality. Pseudogenes of this gene have been found on chromosomes 7 and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Uniprot Description
NLRP5: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. Belongs to the NLRP family.
Protein type: Nucleolus
Cellular Component: protein complex; apical cortex; mitochondrion; cytoplasm; nucleolus; cell cortex; cytosol; nucleus
Molecular Function: protein binding; nucleotide binding; ATP binding
Biological Process: organ morphogenesis; regulation of RNA stability; cellular protein complex assembly; fertilization; in utero embryonic development; regulation of protein stability; embryo implantation
Research Articles on NLRP5
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Product Notes
The Mouse NLRP5 nlrp5 (Catalog #AAA9318358) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318358 ELISA Kit recognizes Mouse NLRP5. It is sometimes possible for the material contained within the vial of "NLR family, pyrin domain containing 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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