NALP5 Blocking Peptide | NLRP5 blocking peptide

NALP5 Peptide

Cat. Num. AAA152825

• Gene Names: NLRP5; MATER; NALP5; PAN11; PYPAF8; CLR19.8
• Applications: Blocking (BL)
• Synonyms: NALP5; NALP5 Peptide; MATER; PAN11; PYPAF8; CLR19.8; NACHT; LRR and PYD domains-containing protein 5; Mater protein homolog; NLR family; pyrin domain containing 5; NLRP5 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 1200

• Applicable Applications for NLRP5 blocking peptide: Blocking (BL)
• Application Notes: NALP5 peptide is used for blocking the activity of NALP5 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 14 amino acids near the carboxy terminus of human NALP5.
• Preparation and Storage: Store NALP5 peptide at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 158321897
• NCBI GeneID: 126206
• NCBI Accession #: NP_703148
• NCBI GenBank Nucleotide #: NM_153447.4
• UniProt Accession #: P59047; Q86W29; A8MTY4
• Molecular Weight: 134,342 Da
• NCBI Official Full Name: NACHT, LRR and PYD domains-containing protein 5
• NCBI Official Synonym Full Names: NLR family, pyrin domain containing 5
• NCBI Official Symbol: NLRP5
• NCBI Official Synonym Symbols: MATER; NALP5; PAN11; PYPAF8; CLR19.8
• NCBI Protein Information: NACHT, LRR and PYD domains-containing protein 5; mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5
• UniProt Protein Name: NACHT, LRR and PYD domains-containing protein 5
• Protein Family: NACHT, LRR and PYD domains-containing protein
• UniProt Gene Name: NLRP5
• UniProt Synonym Gene Names: MATER; NALP5
• UniProt Entry Name: NALP5_HUMAN

NCBI Description

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

NLRP5: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. Belongs to the NLRP family.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: protein complex; mitochondrion; apical cortex; nucleolus; cytosol

Molecular Function: ATP binding

Biological Process: regulation of RNA stability; organ morphogenesis; fertilization; cellular protein complex assembly; in utero embryonic development; regulation of protein stability; embryo implantation