NALP13 Blocking Peptide | NLRP13 blocking peptide

NALP13 Peptide

Cat. Num. AAA151823

• Gene Names: NLRP13; NOD14; PAN13; NALP13; CLR19.7
• Applications: Blocking (BL)
• Synonyms: NALP13; NALP13 Peptide; NOD14; PAN13; CLR19.7; NACHT; LRR and PYD domains-containing protein 13; Nucleotide-binding oligomerization domain protein 14; NLR family; pyrin domain containing 13; NLRP13 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 1043

• Applicable Applications for NLRP13 blocking peptide: Blocking (BL)
• Application Notes: NALP13 peptide is used for blocking the activity of NALP13 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 19 amino acids near the amino terminus of human NALP13.
• Preparation and Storage: Store NALP13 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 119592826
• NCBI GeneID: 126204
• UniProt Accession #: Q86W25; Q7RTR5
• Molecular Weight: 118,884 Da
• NCBI Official Full Name: NACHT, leucine rich repeat and PYD containing 13, isoform CRA_b, partial
• NCBI Official Synonym Full Names: NLR family, pyrin domain containing 13
• NCBI Official Symbol: NLRP13
• NCBI Official Synonym Symbols: NOD14; PAN13; NALP13; CLR19.7
• NCBI Protein Information: NACHT, LRR and PYD domains-containing protein 13; NACHT, LRR and PYD containing protein 13; NACHT, leucine rich repeat and PYD containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
• UniProt Protein Name: NACHT, LRR and PYD domains-containing protein 13
• Protein Family: NACHT, LRR and PYD domains-containing protein
• UniProt Gene Name: NLRP13
• UniProt Synonym Gene Names: NALP13; NOD14
• UniProt Entry Name: NAL13_HUMAN

NCBI Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]

Uniprot Description

NLRP13: Involved in inflammation (Potential). Belongs to the NLRP family.

Chromosomal Location of Human Ortholog: 19q13.43

Molecular Function: ATP binding