Western Blot (WB)
(Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.)
Rabbit anti-Human NALP13 Polyclonal Antibody | anti-NLRP13 antibody
NALP13 Antibody
Gene Names
NLRP13; NOD14; PAN13; NALP13; CLR19.7
Reactivity
Human
Applications
ELISA, Western Blot, Immunocytochemistry, Immunofluorescence
Purity
NALP13 Antibody is affinity chromatography purified via peptide column.
Synonyms
NALP13; Polyclonal Antibody; NALP13 Antibody; NOD14; PAN13; CLR19.7; NACHT; LRR and PYD domains-containing protein 13; Nucleotide-binding oligomerization domain protein 14; NLR family; pyrin domain containing 13; anti-NLRP13 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
NALP13 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1043
Applicable Applications for anti-NLRP13 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
NALP13 antibody can be used for detection of NALP13 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.
Buffer
NALP13 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
NALP13 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.)
Western Blot (WB)
(Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.)
Immunocytochemistry (IHC)
(Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.)
Immunocytochemistry (IHC)
(Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.)
Related Product Information for anti-NLRP13 antibody
NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
118,884 Da
NCBI Official Full Name
NACHT, leucine rich repeat and PYD containing 13, isoform CRA_b, partial
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 13
NCBI Official Symbol
NLRP13
NCBI Official Synonym Symbols
NOD14; PAN13; NALP13; CLR19.7
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 13; NACHT, LRR and PYD containing protein 13; NACHT, leucine rich repeat and PYD containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 13
Protein Family
UniProt Gene Name
NLRP13
UniProt Synonym Gene Names
NALP13; NOD14
UniProt Entry Name
NAL13_HUMAN
NCBI Description
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
Uniprot Description
NLRP13: Involved in inflammation (Potential). Belongs to the NLRP family.
Chromosomal Location of Human Ortholog: 19q13.43
Molecular Function: ATP binding
Research Articles on NLRP13
Similar Products
Product Notes
The NLRP13 nlrp13 (Catalog #AAA150278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NALP13 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NALP13 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). NALP13 antibody can be used for detection of NALP13 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the NLRP13 nlrp13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALP13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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