SDS-PAGE
CD112 / Nectin-2 / PVRL2 Recombinant Protein | CD112 recombinant protein
Recombinant Mouse CD112 / Nectin-2 / PVRL2 Protein (His tag)
SDS-PAGE
SDS-PAGE
Description: A DNA sequence encoding the mouse PVRL2 (NP_033016.3) extracellular domain (Met 1-Gly 351) was fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
Uniprot Description
nectin 2: Probable cell adhesion protein. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7 A3|7 9.94 cM
Cellular Component: apical junction complex; cell surface; focal adhesion; integral to membrane; integral to plasma membrane; intercellular junction; plasma membrane; zonula adherens
Molecular Function: cell adhesion molecule binding; protein binding; protein homodimerization activity; receptor activity; receptor binding
Biological Process: acrosome formation; adhesion to host; cell part morphogenesis; cell recognition; cytoskeleton organization and biogenesis; establishment of mitochondrion localization; fertilization; heterophilic cell adhesion; homophilic cell adhesion; positive regulation of immunoglobulin mediated immune response; positive regulation of mast cell activation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; regulation of virion penetration into host cell; sperm mitochondrion organization and biogenesis; spermatid development; spermatid nuclear differentiation; susceptibility to natural killer cell mediated cytotoxicity; viral envelope fusion with host membrane; virion attachment, binding of host cell surface coreceptor
Research Articles on CD112
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Product Notes
The CD112 nectin2 (Catalog #AAA2547038) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse PVRL2 comprises 331 amino acids with a predicted molecular mass of 36 kDa. As a result of glycosylation, it migrates as an approximately 40-45 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CD112 nectin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD112 / Nectin-2 / PVRL2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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