SDS-PAGE
CD112 / Nectin-2 / PVRL2 Recombinant Protein | CD112 recombinant protein
Recombinant Rat CD112 / Nectin-2 / PVRL2 Protein (His tag)
Gene Names
Bcam; Lu
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CD112 / Nectin-2 / PVRL2; Recombinant Rat CD112 / Nectin-2 / PVRL2 Protein (His tag); PVRL2; CD112 recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
624
Application Notes
The recombinant rat PVRL2 comprises 331 amino acids and predicts a molecular mass of 36 kDa. The apparent molecular mass of the recombinant protein is approximately 46 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Gln 32
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for CD112 recombinant protein
Background: Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
Description: A DNA sequence encoding the rat PVRL2 (Q9ESS6) (Met1-Gly351) was expressed, fused with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the rat PVRL2 (Q9ESS6) (Met1-Gly351) was expressed, fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,512 Da
NCBI Official Full Name
basal cell adhesion molecule
NCBI Official Synonym Full Names
basal cell adhesion molecule (Lutheran blood group)
NCBI Official Symbol
Bcam
NCBI Official Synonym Symbols
Lu
NCBI Protein Information
basal cell adhesion molecule
UniProt Protein Name
Basal cell adhesion molecule
UniProt Gene Name
Bcam
UniProt Synonym Gene Names
Lu
NCBI Description
may act as an adhesion molecule and receptor for laminin [RGD, Feb 2006]
Uniprot Description
Lu: Laminin alpha-5 receptor. May mediate intracellular signaling.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: cell surface; plasma membrane
Molecular Function: laminin binding; laminin receptor activity; protein C-terminus binding
Biological Process: cell adhesion; cell-matrix adhesion
Research Articles on CD112
Similar Products
Product Notes
The CD112 bcam (Catalog #AAA2547341) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant rat PVRL2 comprises 331 amino acids and predicts a molecular mass of 36 kDa. The apparent molecular mass of the recombinant protein is approximately 46 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the CD112 bcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD112 / Nectin-2 / PVRL2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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