Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Arylamine N-acetyltransferase 2 (NAT2) Recombinant Protein | NAT2 recombinant protein

Recombinant Human Arylamine N-acetyltransferase 2 (NAT2)

Gene Names
NAT2; AAC2; PNAT; NAT-2
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Arylamine N-acetyltransferase 2 (NAT2); Recombinant Human Arylamine N-acetyltransferase 2 (NAT2); Arylamide acetylase 2; NAT2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Sequence Positions
Full Length, 1-290aa
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Related Product Information for NAT2 recombinant protein
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
10
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49.52 kDa
NCBI Official Full Name
arylamine N-acetyltransferase 2
NCBI Official Synonym Full Names
N-acetyltransferase 2
NCBI Official Symbol
NAT2
NCBI Official Synonym Symbols
AAC2; PNAT; NAT-2
NCBI Protein Information
arylamine N-acetyltransferase 2
UniProt Protein Name
Arylamine N-acetyltransferase 2
UniProt Gene Name
NAT2
UniProt Synonym Gene Names
AAC2; NAT-2; PNAT

NCBI Description

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]

Uniprot Description

NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Acetyltransferase; EC 2.3.1.5; Secondary Metabolites Metabolism - caffeine; Translation; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity; protein binding

Biological Process: xenobiotic metabolic process

Disease: Acetylation, Slow

Research Articles on NAT2

Similar Products

Product Notes

The NAT2 nat2 (Catalog #AAA9424143) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-290aa. The Recombinant Human Arylamine N-acetyltransferase 2 (NAT2) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Arylamine N-acetyltransferase 2 (NAT2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.