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Western Blot (WB) (Western blotAll lanes: NAT2 antibody at 6ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 34 kDaObserved band size: 34 kDa)

Rabbit anti-Human, mouse NAT2 Polyclonal Antibody | anti-NAT2 antibody

NAT2 Antibody

Gene Names
NAT2; AAC2; PNAT; NAT-2
Reactivity
Human, mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
NAT2; Polyclonal Antibody; NAT2 Antibody; Arylamine N-acetyltransferase 2 (EC:2.3.1.5); AAC2; Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT; anti-NAT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
290
Applicable Applications for anti-NAT2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
Immunogen
Recombinant human Arylamine N-acetyltransferase 2 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47227 / sc-47228 / sc-47231
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: NAT2 antibody at 6ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 34 kDaObserved band size: 34 kDa)

Western Blot (WB) (Western blotAll lanes: NAT2 antibody at 6ug/ml+ Mouse brain tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 34 kDaObserved band size: 34 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7005384 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer using MBS7005384 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of A549 cells using MBS7005384 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of A549 cells using MBS7005384 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-NAT2 antibody
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
10
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,542 Da
NCBI Official Full Name
arylamine N-acetyltransferase 2
NCBI Official Synonym Full Names
N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCBI Official Symbol
NAT2
NCBI Official Synonym Symbols
AAC2; PNAT; NAT-2
NCBI Protein Information
arylamine N-acetyltransferase 2
UniProt Protein Name
Arylamine N-acetyltransferase 2
UniProt Gene Name
NAT2
UniProt Synonym Gene Names
AAC2; NAT-2; PNAT
UniProt Entry Name
ARY2_HUMAN

NCBI Description

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]

Uniprot Description

NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Translation; Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase; Secondary Metabolites Metabolism - caffeine; EC 2.3.1.5

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity; protein binding

Biological Process: xenobiotic metabolic process

Disease: Acetylation, Slow

Research Articles on NAT2

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Product Notes

The NAT2 nat2 (Catalog #AAA7005384) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAT2 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NAT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the NAT2 nat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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