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Mucin 21 (MUC21) Recombinant Protein | MUC21 recombinant protein

Recombinant Mucin 21 (MUC21)

Gene Names
MUC21; MUC-21; KMQK697; C6orf205
Reactivity
Human
Applications
SDS-Page, Western Blot
Purity
> 95%
Synonyms
Mucin 21 (MUC21); Recombinant Mucin 21 (MUC21); C6orf205; Epiglycanin; MUC21 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Human
Purity/Purification
> 95%
Form/Format
Freeze-dried powder
Sequence Length
566
Applicable Applications for MUC21 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Expression System
Prokaryotic expression
Tag
N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Fragment
Ser505~Pro566

SDS-Page

SDS-Page
Product Categories/Family for MUC21 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted Molecular Weight: 10.6kDa
NCBI Official Full Name
mucin-21 isoform 1
NCBI Official Synonym Full Names
mucin 21, cell surface associated
NCBI Official Symbol
MUC21
NCBI Official Synonym Symbols
MUC-21; KMQK697; C6orf205
NCBI Protein Information
mucin-21
UniProt Protein Name
Mucin-21
Protein Family
UniProt Gene Name
MUC21
UniProt Synonym Gene Names
C6orf205; MUC-21

NCBI Description

This gene encodes a large membrane-bound glycoprotein which is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The encoded protein contains an N-terminal signal sequence, an extracellular mucin domain, a stem domain, a transmembrane domain, and a C-terminal cytoplasmic tail domain. The mucin domain contains O-glycosylation sites and is polymorphic with isoforms containing a variable number of nonidentical proline-, threonine-, and serine-rich tandem repeats of 15 amino acids each. The aberrent expression of this gene is associated with lung adenocarcinoma. [provided by RefSeq, May 2017]

Uniprot Description

MUC21: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: Golgi lumen; integral component of membrane; plasma membrane

Biological Process: negative regulation of cell-cell adhesion; O-glycan processing; stimulatory C-type lectin receptor signaling pathway

Research Articles on MUC21

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Product Notes

The MUC21 muc21 (Catalog #AAA2097691) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Mucin 21 (MUC21) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mucin 21 (MUC21) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the MUC21 muc21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mucin 21 (MUC21), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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