NCBI and Uniprot Product Information
Uniprot Description
MTBP: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Belongs to the MTBP family.
Protein type: Ubiquitin conjugating system
Cellular Component: chromatin; kinetochore
Molecular Function: protein binding
Biological Process: cell cycle; cell cycle arrest; negative regulation of cell proliferation; negative regulation of mitosis; traversing start control point of mitotic cell cycle
Research Articles on Mtbp
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Product Notes
The Mouse Mtbp mtbp (Catalog #AAA2882626) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882626 ELISA Kit recognizes Mouse Mtbp. It is sometimes possible for the material contained within the vial of "Mdm2-binding protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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