SDS-Page
MSTN recombinant protein
MSTN, 267-375aa, Human, His tag, E Coli (Denatured)
Gene Names
MSTN; GDF8; MSLHP
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
MSTN; 267-375aa; Human; His tag; E Coli (Denatured); Growth/differentiation factor 8; Myostatin; GDF8; MSLHP; MSTN recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid, In 20mM Tris-HCl (pH 8.0) containing 10% glycerol
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMDFGLD CDEHSTESRC CRYPLTVDFE AFGWDWIIAP KRYKANYCSG ECEFVFLQKY PHTHLVHQAN PRGSAGPCCT PTKMSPINML YFNGKEQIIY GKIPAMVVDR CGCS
Sequence Length
375
Applicable Applications for MSTN recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles
SDS-Page
SDS-Page
Related Product Information for MSTN recombinant protein
MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Recombinant human MSTN, fused to His-tag at N-terminus, was expressed in E Coli.
Product Categories/Family for MSTN recombinant protein
References
Hill J.J., et al. (2003) Mol. Endocrinol. 17:1144-1154
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15.1 kDa (134aa)
NCBI Official Full Name
growth/differentiation factor 8 preproprotein
NCBI Official Synonym Full Names
myostatin
NCBI Official Symbol
MSTN
NCBI Official Synonym Symbols
GDF8; MSLHP
NCBI Protein Information
growth/differentiation factor 8
UniProt Protein Name
Growth/differentiation factor 8
Protein Family
UniProt Gene Name
MSTN
UniProt Synonym Gene Names
GDF8; GDF-8
NCBI Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Uniprot Description
Acts specifically as a negative regulator of skeletal muscle growth.
Research Articles on MSTN
Similar Products
Product Notes
The MSTN mstn (Catalog #AAA205998) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's MSTN can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the MSTN mstn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMDFGLD CDEHSTESRC CRYPLTVDFE AFGWDWIIAP KRYKANYCSG ECEFVFLQKY PHTHLVHQAN PRGSAGPCCT PTKMSPINML YFNGKEQIIY GKIPAMVVDR CGCS. It is sometimes possible for the material contained within the vial of "MSTN, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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