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Human myelin protein zero-like 1 ELISA Kit | MPZL1 elisa kit

Human Myelin protein zero-like protein 1, MPZL1 ELISA Kit

Gene Names
MPZL1; PZR; PZRa; PZRb; PZR1b; MPZL1b
Reactivity
Human
Synonyms
myelin protein zero-like 1; Human Myelin protein zero-like protein 1; MPZL1 ELISA Kit; Human Myelin protein zero-like protein 1 (MPZL1) ELISA kit; FLJ21047; MPZL1b; PZR; PZR1b; PZRa; PZRb; immunoglobulin family transmembrane protein; protein zero related; MPZL1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,082 Da
NCBI Official Full Name
myelin protein zero-like protein 1 isoform c
NCBI Official Synonym Full Names
myelin protein zero-like 1
NCBI Official Symbol
MPZL1
NCBI Official Synonym Symbols
PZR; PZRa; PZRb; PZR1b; MPZL1b
NCBI Protein Information
myelin protein zero-like protein 1; protein zero related; protein zero-related; immunoglobulin family transmembrane protein
UniProt Protein Name
Myelin protein zero-like protein 1
UniProt Gene Name
MPZL1
UniProt Synonym Gene Names
PZR; UNQ849/PRO1787
UniProt Entry Name
MPZL1_HUMAN

Uniprot Description

PZR: an immunoglobulin superfamily cell surface protein. Contains two tyrosine-based inhibition motifs (ITIMs) responsible for binding of SHP-2. When phosphorylated, it can specifically bind SHP-2, blocking its translocation, and interupting its function. Treatment of several cell lines with ConA caused tyrosine phosphorylation of PZR. Two alternatively spliced isoforms have been reported. One isoform, PZR1b, lacks the ITIMs and has a dominant negative effect upon full-length PZR and its recruitment of SHP-2.

Protein type: Membrane protein, integral; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: focal adhesion; cell surface; integral to plasma membrane

Molecular Function: protein binding; structural molecule activity

Biological Process: cell-cell signaling; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on MPZL1

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Product Notes

The Human MPZL1 mpzl1 (Catalog #AAA9320234) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320234 ELISA Kit recognizes Human MPZL1. It is sometimes possible for the material contained within the vial of "myelin protein zero-like 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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