Testing Data
Mouse anti-Human CD45C Antibody | anti-CD45C antibody
Mouse Anti-Human CD45-APC
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoblot, Western Blot
Synonyms
CD45C; Mouse Anti-Human CD45-APC; LCA; T200; Ly5; anti-CD45C antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1kappa
Clone Number
2D1
Specificity
Human CD45
Form/Format
Supplied in PBS/NaN3 and a stabilizing agent
Applicable Applications for anti-CD45C antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoblotting (IB)
Volume
1.0 mL
Immunogen
Human peripheral blood mononuclear cells
Conjugate
APC (Allophycocyanin)
Isotype Control
Mouse IgG1-APC
Preparation and Storage
Store at 2-8 degree C.
Testing Data
Testing Data
Related Product Information for anti-CD45C antibody
CD45, also known as the leukocyte common antigen (LCA), exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.
References
1. Gillitzer R, Berger R, Moll H. A reliable method for simultaneous demonstration of two antigens using a novel combination of immunogold-silver staining and immunoenzymatic labeling. J Histochem Cytochem. 1990;38:307-13. (IHC-FS). 2. Nickoloff BJ, Kunkel SL, Burdick M, Strieter RM. Severe combined immunodeficiency mouse and human psoriatic skin chimeras. Validation of a new animal model. Am J Pathol. 1995;146:580-8. (IHC-FS). 3. Ménétrier-Caux C, Bain C, Favrot MC, Duc A, Blay JY. Renal cell carcinoma induces interleukin 10 and prostaglandin E2 production by monocytes. Br J Cancer. 1999;79:119-30. (IHC-FS). 4. Charbord P, Tavian M, Humeau L, Péault B. Early ontogeny of the human marrow from long bones: an immunohistochemical study of hematopoiesis and its microenvironment. Blood. 1996;87:4109-19. (IHC-PS). 5. Poggi A, Pardi R, Pella N, Morelli L, Sivori S, Vitale M, et al. CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules. Eur J Immunol. 1993;23:2454-63. (IP, WB). 6. Lazarovits AI, Osman N, Le Feuvre CE, Ley SC, Crumpton MJ. CD7 is associated with CD3 and CD45 on human T cells. J Immunol. 1994;153:3956-66. (IP, FC)
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Product Notes
The CD45C (Catalog #AAA679325) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CD45-APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD45C can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoblotting (IB). Researchers should empirically determine the suitability of the CD45C for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD45C, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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