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Western Blot (WB) (All lanes: Carbonyl reductase [NADPH] 3 antibody at 10ug/mlLane 1:Hela whole cell lysateLane 2:K562 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 31kDaObserved band size: 31kDa)

Rabbit anti-Human Carbonyl reductase [NADPH] 3 Polyclonal Antibody | anti-CBR3 antibody

Rabbit anti-human Carbonyl reductase [NADPH] 3 polyclonal Antibody(CBR3)

Gene Names
CBR3; hCBR3; SDR21C2; HEL-S-25
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Carbonyl reductase [NADPH] 3; Polyclonal Antibody; Rabbit anti-human Carbonyl reductase [NADPH] 3 polyclonal Antibody(CBR3); NADPH-dependent carbonyl reductase 3; CBR3; anti-CBR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
277
Applicable Applications for anti-CBR3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Carbonyl reductase [NADPH] 3 protein (118-277aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-70218 / sc-70220 / sc-292142
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(All lanes: Carbonyl reductase [NADPH] 3 antibody at 10ug/mlLane 1:Hela whole cell lysateLane 2:K562 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 31kDaObserved band size: 31kDa)

Western Blot (WB) (All lanes: Carbonyl reductase [NADPH] 3 antibody at 10ug/mlLane 1:Hela whole cell lysateLane 2:K562 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 31kDaObserved band size: 31kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS1497578 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS1497578 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS1497578 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney using MBS1497578 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human spleen using MBS1497578 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human spleen using MBS1497578 at dilution 1:100)
Related Product Information for anti-CBR3 antibody
Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
874
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,850 Da
NCBI Official Full Name
carbonyl reductase
NCBI Official Synonym Full Names
carbonyl reductase 3
NCBI Official Symbol
CBR3
NCBI Official Synonym Symbols
hCBR3; SDR21C2; HEL-S-25
NCBI Protein Information
carbonyl reductase [NADPH] 3
UniProt Protein Name
Carbonyl reductase [NADPH] 3
Protein Family
UniProt Gene Name
CBR3
UniProt Entry Name
CBR3_HUMAN

NCBI Description

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

Uniprot Description

CBR3: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.184; Lipid Metabolism - arachidonic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; cytosol; extracellular space; nucleoplasm

Molecular Function: 3-keto sterol reductase activity; carbonyl reductase (NADPH) activity

Biological Process: cognition; phylloquinone catabolic process

Research Articles on CBR3

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Product Notes

The CBR3 cbr3 (Catalog #AAA1497578) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Carbonyl reductase [NADPH] 3 polyclonal Antibody(CBR3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Carbonyl reductase [NADPH] 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the CBR3 cbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Carbonyl reductase [NADPH] 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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