Mouse TTK protein kinase ELISA Kit | TTK elisa kit
Mouse Dual specificity protein kinase TTK, TTK ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TTK: a dual-specificity protein kinase orthologous to the yeast monopolar spindle (Mps1) kinase that is required for spindle pole duplication and the spindle checkpoint but not for centrosome duplication. Localized to centrosomes, kinetochores and nuclear pores. Its enzymatic activity is required for the recruitment of Mad1, Mad2, Bub1 and Bub3 to the kinetochore. Mps1 mRNA levels change little throughout the cell cycle, but its protein expression varies during the cell cycle. Overexpression arrests cells in metaphase by activating the checkpoint.
Protein type: EC 2.7.12.1; Protein kinase, Other; Kinase, protein; Protein kinase, dual-specificity (non-receptor); Cancer Testis Antigen (CTA); Other group; TTK family
Cellular Component: membrane
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; protein serine/threonine/tyrosine kinase activity; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: mitotic cell cycle checkpoint; phosphorylation; protein amino acid phosphorylation; chromosome separation
Research Articles on TTK
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Product Notes
The Mouse TTK ttk (Catalog #AAA9341334) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341334 ELISA Kit recognizes Mouse TTK. It is sometimes possible for the material contained within the vial of "TTK protein kinase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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