Typical Testing Data/Standard Curve (for reference only)
Mouse Transforming Growth Factor Beta 3 (TGFb3) ELISA Kit | TGFb3 elisa kit
Mouse Transforming Growth Factor Beta 3 (TGFb3) Mini Samples ELISA Kit
No significant cross-reactivity or interference between Mini Samples Transforming Growth Factor Beta 3 (TGFb3) and analogues was observed.
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Mini Samples Transforming Growth Factor Beta 3 (TGFb3) were tested on 3 different plates, 8 replicates in each plate.
CV(%) = SD/meanX100
Intra-Assay: CV<10%
Inter-Assay: CV<12%
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Homozygous knockout mice for this gene exhibit cleft palate, delayed pulmonary development and neonatal death. [provided by RefSeq, Aug 2016]
Uniprot Description
TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.
Protein type: Motility/polarity/chemotaxis; Secreted; Cell development/differentiation; Secreted, signal peptide; Ligand, receptor tyrosine kinase
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cell surface; cell soma; cytoplasm; T-tubule; extracellular region; nucleus; secretory granule
Molecular Function: identical protein binding; growth factor activity; transforming growth factor beta binding; protein heterodimerization activity; punt binding; cytokine activity; transforming growth factor beta receptor binding
Biological Process: positive regulation of apoptosis; activation of MAPK activity; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; palate development; SMAD protein nuclear translocation; negative regulation of cell proliferation; mammary gland development; transforming growth factor beta receptor signaling pathway; embryonic neurocranium morphogenesis; negative regulation of neuron apoptosis; cell growth; positive regulation of filopodium formation; intercellular junction assembly and maintenance; in utero embryonic development; embryonic development; organ morphogenesis; positive regulation of protein secretion; negative regulation of DNA replication; response to estrogen stimulus; regulation of MAPKKK cascade; positive regulation of cell division; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; response to progesterone stimulus; alveolus development; positive regulation of DNA replication; growth
Research Articles on TGFb3
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Product Notes
The Mouse TGFb3 tgfb3 (Catalog #AAA2708373) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2708373 ELISA Kit recognizes Mouse TGFb3. AAA Biotech's Transforming Growth Factor Beta 3 (TGFb3) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the TGFb3 tgfb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor Beta 3 (TGFb3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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