Typical Testing Data/Standard Curve (for reference only)
Mouse TGFBI ELISA Kit | TGFBI elisa kit
Mouse TGFBI ELISA Kit
Gene Names
Tgfbi; 68kDa; big-h3; Beta-ig; AI181842; AI747162
Reactivity
Mouse
Synonyms
TGFBI; Mouse TGFBI ELISA Kit; BIGH3; Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP; TGFBI elisa kit
Reactivity
Mouse
Specificity
The Mouse TGFBI ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse TGFBI proteins within the range of 156 pg/ml - 10000 pg/ml.
Sequence Length
683
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<5 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for TGFBI elisa kit
Principle of the Assay: The Mouse TGFBI ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TGFBI in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Mouse TGFBI coated on a 96-well plate. Standards and samples are pipetted into the wells and TGFBI present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse TGFBI antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of TGFBI bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
Background: Transforming growth factor, beta-induced, 68kDa, also known as TGFBI (initially called BIGH3, BIG-H3), is a protein which in humans is encoded by the TGFBI gene. It is mapped to 5q31.1. This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,597 Da
NCBI Official Full Name
transforming growth factor-beta-induced protein ig-h3
NCBI Official Synonym Full Names
transforming growth factor, beta induced
NCBI Official Symbol
Tgfbi
NCBI Official Synonym Symbols
68kDa; big-h3; Beta-ig; AI181842; AI747162
NCBI Protein Information
transforming growth factor-beta-induced protein ig-h3
UniProt Protein Name
Transforming growth factor-beta-induced protein ig-h3
Protein Family
UniProt Gene Name
Tgfbi
UniProt Synonym Gene Names
Beta ig-h3
UniProt Entry Name
BGH3_MOUSE
Uniprot Description
betaIG-H3: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. By TGFB1. Highly expressed in the corneal epithelium.
Protein type: Cell adhesion; Extracellular matrix; Secreted; Secreted, signal peptide
Cellular Component: basement membrane; extracellular matrix; extracellular space; proteinaceous extracellular matrix; trans-Golgi network
Molecular Function: cell adhesion molecule binding; collagen binding; extracellular matrix binding
Biological Process: cell adhesion; extracellular matrix organization and biogenesis
Research Articles on TGFBI
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Product Notes
The Mouse TGFBI tgfbi (Catalog #AAA8248462) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8248462 ELISA Kit recognizes Mouse TGFBI. It is sometimes possible for the material contained within the vial of "TGFBI, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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