Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Syntaxin-1A (STX1A) Standard Curve.)
Mouse Syntaxin-1A (STX1A) ELISA Kit | STX1A elisa kit
Mouse Syntaxin-1A (STX1A) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Syntaxin-1A (STX1A) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Syntaxin-1A (STX1A) Standard Curve.)
Background: Syntaxin-1A is a protein encoded by the STX1A gene.Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
Uniprot Description
STX1A: a type IV membrane protein involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. Three splice variant isoforms have been described.
Protein type: Membrane protein, integral; Vesicle
Cellular Component: neuron projection; protein complex; synaptic vesicle membrane; cell; integral to membrane; actomyosin; endomembrane system; intracellular organelle; secretory granule; SNARE complex; synaptic vesicle; membrane; plasma membrane; synapse; cytoplasmic vesicle; intracellular; cell junction
Molecular Function: protein binding, bridging; SNAP receptor activity; protein domain specific binding; ATP-dependent protein binding; SNARE binding; protein binding; chloride channel inhibitor activity; myosin binding; protein heterodimerization activity; myosin head/neck binding; protein N-terminus binding; calcium channel inhibitor activity; glycoprotein binding; calcium-dependent protein binding; kinase binding
Biological Process: response to gravity; exocytosis; positive regulation of neurotransmitter secretion; calcium ion-dependent exocytosis; synaptic vesicle fusion to presynaptic membrane; vesicle-mediated transport; regulation of exocytosis; intracellular protein transport; vesicle docking; transport; neurotransmitter transport; secretion by cell; positive regulation of exocytosis
Research Articles on STX1A
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Product Notes
The Mouse STX1A stx1a (Catalog #AAA9716885) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716885 ELISA Kit recognizes Mouse STX1A. It is sometimes possible for the material contained within the vial of "Syntaxin-1A (STX1A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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