Typical Testing Data/Standard Curve (for reference only)
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Mouse Rho-Related GTP-Binding Protein RhoC (RHOC) ELISA Kit | RHOC elisa kit
Mouse Rho-Related GTP-Binding Protein RhoC (RHOC) ELISA Kit
Gene Names
Rhoc; Arh9; Arhc; AI324259
Reactivity
Mouse
Synonyms
Rho-Related GTP-Binding Protein RhoC (RHOC); Mouse Rho-Related GTP-Binding Protein RhoC (RHOC) ELISA Kit; RHOC; RP11-426L16.4; ARH9; ARHC; H9; MGC1448; MGC61427; RHOH9; OTTHUMP00000013802; OTTHUMP00000013805; OTTHUMP00000013807; RAS-related homolog 9; Rho-related GTP-binding protein RhoC; oncogene RHO H9; rhoC GTPa; RHOC elisa kit
Reactivity
Mouse
Sequence Length
193
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
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Typical Testing Data/Standard Curve (for reference only)
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Related Product Information for RHOC elisa kit
Principle of the Assay: Mouse Rho-related GTP-binding protein RhoC (RHOC) ELISA Kit employs a two-site sandwich ELISA to quantitate RHOC in samples. An antibody specific for RHOC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RHOC present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Mouse RHOC detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of RHOC bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: RhoC (Ras homolog gene family, member C) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases.It cycles between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. It is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis.
Background/Introduction: RhoC (Ras homolog gene family, member C) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases.It cycles between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. It is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
rho-related GTP-binding protein RhoC
NCBI Official Synonym Full Names
ras homolog family member C
NCBI Official Symbol
Rhoc
NCBI Official Synonym Symbols
Arh9; Arhc; AI324259
NCBI Protein Information
rho-related GTP-binding protein RhoC
UniProt Protein Name
Rho-related GTP-binding protein RhoC
Protein Family
UniProt Gene Name
Rhoc
UniProt Synonym Gene Names
Arhc; SIG-61
UniProt Entry Name
RHOC_MOUSE
Uniprot Description
RHOC: a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Controls the reorganization of actins into podosomes. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders.
Protein type: G protein, monomeric, Rho; G protein, monomeric; G protein; Motility/polarity/chemotaxis
Cellular Component: membrane; plasma membrane; intracellular; cytosol; nucleus; cleavage furrow
Molecular Function: protein binding; signal transducer activity; GTP binding; nucleotide binding
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; apical junction assembly; small GTPase mediated signal transduction; cytokinesis; signal transduction
Research Articles on RHOC
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Product Notes
The Mouse RHOC rhoc (Catalog #AAA9717110) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717110 ELISA Kit recognizes Mouse RHOC. It is sometimes possible for the material contained within the vial of "Rho-Related GTP-Binding Protein RhoC (RHOC), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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