Typical Testing Data/Standard Curve (for reference only)
Mouse Peroxidasin Homolog (PXDN) ELISA Kit | PXDN elisa kit
Mouse Peroxidasin Homolog (PXDN) ELISA Kit
Gene Names
Pxdn; VPO1; C85409; mKIAA0230; E330004E07; 2310075M15Rik
Reactivity
Mouse
Synonyms
Peroxidasin Homolog (PXDN); Mouse Peroxidasin Homolog (PXDN) ELISA Kit; PXDN; D2S448; D2S448E; KIAA0230; MG50; PRG2; PXN; VPO; p53-responsive gene 2; peroxidasin; PXDN elisa kit
Reactivity
Mouse
Sequence Length
1475
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for PXDN elisa kit
Principle of the Assay: Mouse Peroxidasin Homolog (PXDN) ELISA Kit employs a two-site sandwich ELISA to quantitate PXDN in samples. An antibody specific for PXDN has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PXDN present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Mouse PXDN detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of PXDN bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: PXDNL belongs to the peroxidase family. PXDNL is moderately expressed, only 28.6% of the average gene in this release, PXDNL contains 23 different gt-ag introns. XPO subfamily. Dysfunction of mitochondria in nerve cells contributes to the neurodegeneration of PD. When cells are infected by the CMV virus, they become resistant to certain mitochondrial toxins that may be important in causing PD. CMV-infected cells produce very high levels of a protein called PXDNL about which very little is known. PXDNL is selectively found in substantia nigra neurons, increasing its levels will detoxify the free radicals produced by malfunctioning mitochondria and thereby protect these neurons.
Background/Introduction: PXDNL belongs to the peroxidase family. PXDNL is moderately expressed, only 28.6% of the average gene in this release, PXDNL contains 23 different gt-ag introns. XPO subfamily. Dysfunction of mitochondria in nerve cells contributes to the neurodegeneration of PD. When cells are infected by the CMV virus, they become resistant to certain mitochondrial toxins that may be important in causing PD. CMV-infected cells produce very high levels of a protein called PXDNL about which very little is known. PXDNL is selectively found in substantia nigra neurons, increasing its levels will detoxify the free radicals produced by malfunctioning mitochondria and thereby protect these neurons.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
peroxidasin homolog
NCBI Official Synonym Full Names
peroxidasin
NCBI Official Symbol
Pxdn
NCBI Official Synonym Symbols
VPO1; C85409; mKIAA0230; E330004E07; 2310075M15Rik
NCBI Protein Information
peroxidasin homolog
UniProt Protein Name
Peroxidasin homolog
UniProt Gene Name
Pxdn
UniProt Synonym Gene Names
Kiaa0230
UniProt Entry Name
PXDN_MOUSE
Uniprot Description
PXDN: Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. Belongs to the peroxidase family. XPO subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide; EC 1.11.1.7; Oxidoreductase
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; endoplasmic reticulum; extracellular region
Molecular Function: peroxidase activity; metal ion binding; extracellular matrix structural constituent; heme binding; oxidoreductase activity
Biological Process: extracellular matrix organization and biogenesis; hydrogen peroxide catabolic process; response to oxidative stress
Research Articles on PXDN
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Product Notes
The Mouse PXDN pxdn (Catalog #AAA9717210) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717210 ELISA Kit recognizes Mouse PXDN. It is sometimes possible for the material contained within the vial of "Peroxidasin Homolog (PXDN), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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