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Mouse IL-21 ELISA Kit | IL-21 elisa kit

IL-21 (Murine) OmniKine ELISA Kit

Gene Names
Il21; IL-21
Reactivity
Mouse
Synonyms
IL-21; IL-21 (Murine) OmniKine ELISA Kit; Interleukin-21; IL-21 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
The OmniKine Murine IL-21 ELISA is capable of recognizing both recombinant and naturally produced Murine IL-21 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: IL-2, IL-4, IL-7, IL-9, IL-15, IL-21
Murine: IL-2, IL-4, IL-7, IL-9, IL-15
Rat: IL-2, IL-4, IL-7, IL-9, IL-15
Form/Format
12 x 8-Well Microstrips
Sequence Length
146
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
46-3000 pg/ml
Sensitivity
46-3000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,811 Da
NCBI Official Full Name
interleukin-21 isoform 2
NCBI Official Synonym Full Names
interleukin 21
NCBI Official Symbol
Il21
NCBI Official Synonym Symbols
IL-21
NCBI Protein Information
interleukin-21
UniProt Protein Name
Interleukin-21
UniProt Gene Name
Il21
UniProt Synonym Gene Names
IL-21

Uniprot Description

IL21: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Cell development/differentiation; Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3|3 B

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; cytokine receptor binding; interleukin-2 receptor binding

Biological Process: B cell apoptosis; cell maturation; immune response; positive regulation of B cell differentiation; positive regulation of B cell proliferation; positive regulation of cell proliferation; positive regulation of cytokine production; positive regulation of interferon-gamma biosynthetic process; positive regulation of interleukin-10 production; positive regulation of interleukin-17 production; positive regulation of natural killer cell cytokine production; positive regulation of natural killer cell differentiation; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of T cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; tyrosine phosphorylation of STAT protein

Research Articles on IL-21

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Product Notes

The Mouse IL-21 il21 (Catalog #AAA9501911) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501911 ELISA Kit recognizes Mouse IL-21. It is sometimes possible for the material contained within the vial of "IL-21, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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