Mouse IL-23 ELISA Kit | IL-23 elisa kit

IL-23 (Murine) OmniKine ELISA Kit

Cat. Num. AAA9502011

• Gene Names: Il23a; p19; IL-23
• Reactivity: Mouse
• Synonyms: IL-23; IL-23 (Murine) OmniKine ELISA Kit; Interleukin-23 subunit alpha/beta; Interleukin-23 subunit p19/p40; IL-23 elisa kit

• Reactivity: Mouse
• Specificity: The OmniKine Murine IL-23 ELISA is capable of recognizing both recombinant and naturally produced Murine IL-23 proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: IL-23, IL-23 p19; Murine: Il-12, IL-12 p35, IL-12/IL-23 p40, IL-12 p40 monomer, IL-12R, IL-23R/Fc Chimera; Rat: IL-12, IL-23
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 196

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 40-2500 pg/ml
• Sensitivity: 40-2500 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Murine IL-23 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine IL-23 proteins within the range of 40-2500 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 13752579
• NCBI GeneID: 83430
• NCBI Accession #: NP_112542.1
• NCBI GenBank Nucleotide #: NM_031252.2
• UniProt Accession #: Q9EQ14; P43432
• Molecular Weight: 22,071 Da
• NCBI Official Full Name: interleukin-23 subunit alpha
• NCBI Official Synonym Full Names: interleukin 23, alpha subunit p19
• NCBI Official Symbol: Il23a
• NCBI Official Synonym Symbols: p19; IL-23
• NCBI Protein Information: interleukin-23 subunit alpha
• UniProt Protein Name: Interleukin-23 subunit alpha
• UniProt Gene Name: Il23a
• UniProt Synonym Gene Names: IL-23 subunit alpha; IL-23-A; IL-23p19

Uniprot Description

IL23A: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Belongs to the IL-6 superfamily.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10|10 D3

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; interleukin-23 receptor binding; protein binding

Biological Process: defense response to Gram-negative bacterium; defense response to virus; immune response; immune system process; inflammatory response; innate immune response; negative regulation of interleukin-10 production; positive regulation of activated T cell proliferation; positive regulation of defense response to virus by host; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-10 production; positive regulation of interleukin-12 production; positive regulation of interleukin-17 production; positive regulation of memory T cell differentiation; positive regulation of natural killer cell proliferation; positive regulation of NK T cell activation; positive regulation of NK T cell proliferation; positive regulation of osteoclast differentiation; positive regulation of T cell mediated cytotoxicity; positive regulation of T cell proliferation; positive regulation of T-helper 1 type immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of tyrosine phosphorylation of STAT protein; regulation of tyrosine phosphorylation of STAT protein; T cell proliferation; tissue remodeling