Typical Testing Data/Standard Curve (for reference only)
Mouse FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB) ELISA Kit | FOSB elisa kit
Mouse FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB) ELISA Kit
Gene Names
FOSB; AP-1; G0S3; GOS3; GOSB
Reactivity
Mouse
Synonyms
FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB); Mouse FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB) ELISA Kit; FOSB; AP-1; DKFZp686C0818; G0S3; GOS3; GOSB; MGC42291; activator protein 1; oncogene FOS-B; FOSB elisa kit
Reactivity
Mouse
Sequence Length
338
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for FOSB elisa kit
Principle of the Assay: Mouse FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB) ELISA Kit employs a two-site sandwich ELISA to quantitate FOSB in samples. An antibody specific for FOSB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FOSB present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Mouse FOSB detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of FOSB bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: Delta FosB is a truncated splice variant of FosB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. "Delta FosB" levels have been found to increase upon the use of cocaine. Each subsequent dose of cocaine will continue to increase the levels of Delta FosB with no ceiling of tolerance. Increasing the levels of Delta FosB has led to increases in "Brain-Derived Neurotrophic Factor" (BDNF) levels, which in turn will increase the number of dendritic
Background/Introduction: Delta FosB is a truncated splice variant of FosB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. "Delta FosB" levels have been found to increase upon the use of cocaine. Each subsequent dose of cocaine will continue to increase the levels of Delta FosB with no ceiling of tolerance. Increasing the levels of Delta FosB has led to increases in "Brain-Derived Neurotrophic Factor" (BDNF) levels, which in turn will increase the number of dendritic
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
FBJ murine osteosarcoma viral oncogene homolog B
NCBI Official Synonym Full Names
FosB proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol
FOSB
NCBI Official Synonym Symbols
AP-1; G0S3; GOS3; GOSB
NCBI Protein Information
protein fosB
Protein Family
NCBI Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Articles on FOSB
Similar Products
Product Notes
The Mouse FOSB (Catalog #AAA9718096) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9718096 ELISA Kit recognizes Mouse FOSB. It is sometimes possible for the material contained within the vial of "FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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