Mouse Interleukin 31 (IL31) CLIA Kit | IL31 clia kit

Mouse Interleukin 31 (IL31) CLIA Kit

Cat. Num. AAA2001015

• Gene Names: IL31; IL-31
• Reactivity: Mouse
• Synonyms: Interleukin 31 (IL31); Mouse Interleukin 31 (IL31) CLIA Kit; IL31 clia kit

• Reactivity: Mouse
• Specificity: This assay has high sensitivity and excellent specificity for detection of Interleukin 31 (IL31).; No significant cross-reactivity or interference between Interleukin 31 (IL31) and analogues was observed.
• Sequence Length: 164

• Assay Type: Double-antibody Sandwich
• Samples: Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and Other Biological Fluids
• Detection Range: 0.55-400pg/mL
• Sensitivity: < 0.19pg/mL
• Application: Chemiluminescent immunoassay for Antigen Detection.
• Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Interleukin 31 (IL31) were tested 20 times on one plate, respectively.
• Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Interleukin 31 (IL31) were tested on 3 different plates, 8 replicates in each plate.
• CV(%) =: SD/meanX100
• Intra-Assay: CV<10%
• Inter-Assay: CV<12%
• Preparation and Storage: The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. ; To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for IL31 clia kit

The microplate provided in this kit has been pre-coated with an antibody specific to Interleukin 31 (IL31). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Interleukin 31 (IL31). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Interleukin 31 (IL31) level in the sample or standard.;

Product Categories/Family for IL31 clia kit

Cytokine; Tumor immunity; Infection immunity; Dermatology

NCBI and Uniprot Product Information

• NCBI GI #: 62122911
• NCBI GeneID: 386653
• NCBI Accession #: NP_001014358.1
• NCBI GenBank Nucleotide #: NM_001014336.1
• UniProt Accession #: Q6EBC2; A2RUQ1
• Molecular Weight: 18,205 Da
• NCBI Official Full Name: interleukin-31
• NCBI Official Synonym Full Names: interleukin 31
• NCBI Official Symbol: IL31
• NCBI Official Synonym Symbols: IL-31
• NCBI Protein Information: interleukin-31
• UniProt Protein Name: Interleukin-31
• Protein Family: Interleukin
• UniProt Gene Name: IL31
• UniProt Synonym Gene Names: IL-31
• UniProt Entry Name: IL31_HUMAN

NCBI Description

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

Uniprot Description

IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: immune system process