Western Blot (WB)
(Western Blot analysis of Human brain tissue using TRPC4AP Monoclonal Antibody at dilution of 1:1000)
Mouse anti-Human TRPC4AP Monoclonal Antibody | anti-TRPC4AP antibody
TRPC4AP Monoclonal Antibody
Gene Names
TRPC4AP; TRUSS; TRRP4AP; PPP1R158; C20orf188
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A purification
Synonyms
TRPC4AP; Monoclonal Antibody; TRPC4AP Monoclonal Antibody; C20orf188; Chromosome 20 open reading frame 188; Protein TAP1; Protein TRUSS; Short transient receptor potential channel 4 associated protein; Short transient receptor potential channel 4-associated protein; TAP1 protein; TNF receptor ubiquitous scaffolding/signaling protein; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; Transient receptor potential cation channel; subfamily C; member 4 associated protein; Trp4 associated protein; Trp4-associated protein; Trpc4 associated protein; Trpc4-associated protein; TRRP4AP; TRUSS; Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein; anti-TRPC4AP antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3
Clone Number
256
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
797
Applicable Applications for anti-TRPC4AP antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:5000
IHC: 1:20-1:200
IHC: 1:20-1:200
Immunogen
Fusion protein of TRPC4AP
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Human brain tissue using TRPC4AP Monoclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of Human brain tissue using TRPC4AP Monoclonal Antibody at dilution of 1:1000)
Related Product Information for anti-TRPC4AP antibody
TRPC4AP, also named as C20orf188 and TRRP4AP, is a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. TRPC4AP participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. The calculated molecular weight of TRPC4AP is 91 kDa. Western blot analysis detected a protein of about 82 kDa expressed in several mouse cell lines and in a human promonocytic cell line.
Product Categories/Family for anti-TRPC4AP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 91kDa
Observed: 82kDa
Observed: 82kDa
NCBI Official Full Name
short transient receptor potential channel 4-associated protein isoform a
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily C member 4 associated protein
NCBI Official Symbol
TRPC4AP
NCBI Official Synonym Symbols
TRUSS; TRRP4AP; PPP1R158; C20orf188
NCBI Protein Information
short transient receptor potential channel 4-associated protein
UniProt Protein Name
Short transient receptor potential channel 4-associated protein
UniProt Gene Name
TRPC4AP
UniProt Synonym Gene Names
C20orf188; TRRP4AP; Trp4-associated protein; Trpc4-associated protein; Protein TRUSS
Uniprot Description
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca2+ storage reduction in response to CHRM1.
Research Articles on TRPC4AP
Similar Products
Product Notes
The TRPC4AP trpc4ap (Catalog #AAA2542101) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TRPC4AP Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPC4AP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:5000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the TRPC4AP trpc4ap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPC4AP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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