Mouse anti-Human TLR3 Monoclonal Antibody
TLR3 (Toll Like Receptor 3) (PE)
Reactivity
Human
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
TLR3; Monoclonal Antibody; TLR3 (Toll Like Receptor 3) (PE); Anti -TLR3 (Toll Like Receptor 3) (PE); anti-TLR3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4H271
Specificity
Recognizes human TLR3 (Toll Like Receptor 3)
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-TLR3 antibody
Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Western Blot and Flow Cytometry.
Dilution: Western Blot: 1-3ug/ml
Flow Cytometry (Intercellular): 2-5 ug/1x10e6 cells
Dilution: Western Blot: 1-3ug/ml
Flow Cytometry (Intercellular): 2-5 ug/1x10e6 cells
Immunogen
KLH-conjugated synthetic peptide of human TLR3.
Positive Control
Human Intestine or Ramos
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-TLR3 antibody
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1) and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described (3). TLR3 cDNA codes for a protein with approximate molecular weight of 120kD (4). TLR3 has a restricted expression pattern being expressed in dendritic cells (DC) (4-6). TLR3 mRNA expression was detected by in situ hybridization in DC and lymph nodes (6). The expression of TLR3 in a single cell type may indicate a specific role for this molecule in a restricted setting.
Product Categories/Family for anti-TLR3 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The TLR3 (Catalog #AAA606707) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TLR3 (Toll Like Receptor 3) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TLR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS). Suitable for use in Western Blot and Flow Cytometry. Dilution: Western Blot: 1-3ug/ml Flow Cytometry (Intercellular): 2-5 ug/1x10e6 cells. Researchers should empirically determine the suitability of the TLR3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
