Western Blot (WB)
(Western Blot showing Tip60 antibody used against truncated Tip60 recombinant protein.)
Mouse TIP60 Monoclonal Antibody | anti-TIP60 antibody
TIP60 antibody
Gene Names
Tip60; 6121; CG6121; DmEG0007.7; Dmel/TIP60; DmelCG6121; DmelTIP60; dmHAG405; dTip60; dTIP60; EG0007.7; EG:EG0007.7; TIP60
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
TIP60; Monoclonal Antibody; TIP60 antibody; Monoclonal TIP60; Anti-TIP60; HTATIP; Histone acetyltransferase KAT5; PLIP; ESA1; TIP 60; TIP-60; HTATIP1; cPLA2; TIP; anti-TIP60 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
3F9
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
541
Applicable Applications for anti-TIP60 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
ELISA: 1:10,000
IHC: 1:200-1:1000
WB: 1:500-1:2000
IHC: 1:200-1:1000
WB: 1:500-1:2000
Biological Significance
TIP60 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Cross-Reactivity
Human
Immunogen
TIP60 antibody was raised in Mouse using a purified recombinant fragment of human TIP60 expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot showing Tip60 antibody used against truncated Tip60 recombinant protein.)
Western Blot (WB)
(Western Blot showing Tip60 antibody used against truncated Tip60 recombinant protein.)
Related Product Information for anti-TIP60 antibody
Mouse monoclonal TIP60 antibody
Product Categories/Family for anti-TIP60 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,234 Da
NCBI Official Full Name
Tip60, isoform A
NCBI Official Symbol
Tip60
NCBI Official Synonym Symbols
6121; CG6121; DmEG0007.7; Dmel/TIP60; DmelCG6121; DmelTIP60; dmHAG405; dTip60; dTIP60; EG0007.7; EG:EG0007.7; TIP60
NCBI Protein Information
CG6121 gene product from transcript CG6121-RA
UniProt Protein Name
Histone acetyltransferase Tip60
Protein Family
UniProt Gene Name
Tip60
UniProt Entry Name
TIP60_DROME
Uniprot Description
Catalytic subunit of the Tip60 chromatin-remodeling complex which is involved in DNA repair. Upon induction of DNA double-strand breaks, acetylates phosphorylated histone H2AV in nucleosomes on 'Lys-4' and exchanges it with unmodified H2AV.
Research Articles on TIP60
Similar Products
Product Notes
The TIP60 tip60 (Catalog #AAA533054) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TIP60 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). ELISA: 1:10,000 IHC: 1:200-1:1000 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TIP60 tip60 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIP60, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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