Western Blot (WB)
(Western blot detection of Thymidine Kinase 1 in K562,Hela cell lysates using Thymidine Kinase 1 Rabbit mAb(1:1000 diluted). Predicted band size:26kDa. Observed band size:26kDa.)
Rabbit anti-Human Thymidine Kinase 1 Monoclonal Antibody | anti-TK1 antibody
Thymidine Kinase 1 Rabbit mAb
IHC: 1:20-1:100
ICC/IF: 1:20
FC/FACS: 1:20
IP: 1:20
Western Blot (WB)
(Western blot detection of Thymidine Kinase 1 in K562,Hela cell lysates using Thymidine Kinase 1 Rabbit mAb(1:1000 diluted). Predicted band size:26kDa. Observed band size:26kDa.)
Western Blot (WB)
(Western blot detection of Thymidine Kinase 1 in K562,Hela cell lysates using Thymidine Kinase 1 Rabbit mAb(1:1000 diluted). Predicted band size:26kDa. Observed band size:26kDa.)
MiscellaneousTwo forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.
NCBI and Uniprot Product Information
Uniprot Description
TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.
Protein type: Nucleotide Metabolism - pyrimidine; EC 2.7.1.21; Xenobiotic Metabolism - drug metabolism - other enzymes; Kinase, other
Chromosomal Location of Human Ortholog: 17q23.2-q25.3
Cellular Component: cytosol
Molecular Function: identical protein binding; nucleoside kinase activity; zinc ion binding; thymidine kinase activity; ATP binding
Biological Process: response to nutrient levels; skeletal muscle cell proliferation; nucleobase, nucleoside and nucleotide metabolic process; response to toxin; liver development; fetal process involved in parturition; deoxyribonucleoside monophosphate biosynthetic process; protein homotetramerization; response to cortisol stimulus; pyrimidine base metabolic process; gut development; response to copper ion; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; thymidine metabolic process; pyrimidine nucleoside salvage; phosphorylation
Research Articles on TK1
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Product Notes
The TK1 tk1 (Catalog #AAA4753065) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Thymidine Kinase 1 Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thymidine Kinase 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP). WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20 FC/FACS: 1:20 IP: 1:20. Researchers should empirically determine the suitability of the TK1 tk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thymidine Kinase 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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