Mouse anti-Human Tau Monoclonal Antibody | anti-tau antibody

Tau, phosphorylated (Ser396)

Cat. Num. AAA633416

• Gene Names: tau; BcDNA:RE16764; CG12881; CG31057; CG5606; DmelCG31057; dtau
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A chromatography
• Synonyms: Tau; Monoclonal Antibody; phosphorylated (Ser396); Anti -Tau; anti-tau antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: 6A193
• Specificity: Specific for PHF-Tau phosphorylated on serine 396. This antibody did not recognize PHF-Tau phoshorylated at other sites, including Ser 400, Thr 403, or Ser 404. Reactivity is confirmed with human PHF-Tau.
• Purity/Purification: Affinity Purified; Purified by Protein A chromatography
• Form/Format: Supplied as a liquid in PBS, pH 7.4, containing 0.1% sodium azide

• Applicable Applications for anti-tau antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 3-5ug/ml; Western Blot: 1-3ug/ml
• Immunogen: Purified human PHF-Tau preparation.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-tau antibody

Alzheimer's disease (AD) is characterized by senile plaques, largely composed of extracellular deposits of Ab peptide, and neurofibrillary tangles (NFT) which are composed of intracellular filamentous aggregates of hyperphosphorylated tau proteins. These tangles represent dense accumulations of distinct paired helical filaments (PHF), in which the major component is a microtubule-associated tau protein. NFTs are biochemically and structurally distinct from the amyloid fibrils in senile plaques. Currently in development are antibodies specific to PHF-tau because of the elevated tau levels found in the cerebrospinal fluid of AD patients. Also, the identification of a number of neurodegenerative diseases that are characterized by tau tangles suggests that tangle formation may initiate as well as contribute to the final step in the

Product Categories/Family for anti-tau antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 21357661
• NCBI GeneID: 326116
• NCBI Accession #: NP_651575.1
• NCBI GenBank Nucleotide #: NM_143318.2
• NCBI Official Full Name: tau
• NCBI Official Symbol: tau
• NCBI Official Synonym Symbols: BcDNA:RE16764; CG12881; CG31057; CG5606; DmelCG31057; dtau
• NCBI Protein Information: CG31057 gene product from transcript CG31057-RA; tau; CG31057-PA; tau-PA
• Protein Family: Tautomerase