Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western Blot detection against Immunogen (36.01kD).)

Mouse anti-Human TAOK3 Monoclonal Antibody | anti-Taok3 antibody

TAOK3 (DPK, JIK, KDS, MAP3K18, Serine/Threonine-protein Kinase TAO3, Cutaneous T-cell Lymphoma-associated Antigen HD-CL-09, Dendritic Cell-derived Protein Kinase, JNK/SAPK-inhibitory Kinase, Jun Kinase-inhibitory Kinase, Kinase from Chicken Homolog A, Tho

Gene Names
Taok3; A130052D22; 2900006A08Rik; A430105I05Rik
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
TAOK3; Monoclonal Antibody; TAOK3 (DPK; JIK; KDS; MAP3K18; Serine/Threonine-protein Kinase TAO3; Cutaneous T-cell Lymphoma-associated Antigen HD-CL-09; Dendritic Cell-derived Protein Kinase; JNK/SAPK-inhibitory Kinase; Jun Kinase-inhibitory Kinase; Kinase from Chicken Homolog A; Tho; Anti -TAOK3 (DPK; anti-Taok3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
4C12
Specificity
Recognizes human TAOK3.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
LNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKNLLERQEREIETFDMESLRMGFGNLVTLDFPKEDYR
Applicable Applications for anti-Taok3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Immunogen
Partial recombinant corresponding to aa809-899 from human TAOK3 (AAH02756) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (36.01kD).)

Western Blot (WB) (Western Blot detection against Immunogen (36.01kD).)

Testing Data

(Detection limit for recombinant GST tagged TAOK3 is ~3ng/ml as a capture antibody.)

Testing Data (Detection limit for recombinant GST tagged TAOK3 is ~3ng/ml as a capture antibody.)
Related Product Information for anti-Taok3 antibody
TAOK3 is a protein that inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
Product Categories/Family for anti-Taok3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
105,336 Da
NCBI Official Full Name
Taok3 protein
NCBI Official Synonym Full Names
TAO kinase 3
NCBI Official Symbol
Taok3
NCBI Official Synonym Symbols
A130052D22; 2900006A08Rik; A430105I05Rik
NCBI Protein Information
serine/threonine-protein kinase TAO3; thousand and one amino acid protein 3
UniProt Protein Name
Serine/threonine-protein kinase TAO3
UniProt Gene Name
Taok3
UniProt Entry Name
TAOK3_MOUSE

Uniprot Description

TAO3: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; Protein kinase, STE; STE group; STE20 family; TAO subfamily

Cellular Component: cytoplasm; intracellular

Molecular Function: transferase activity; protein serine/threonine kinase activity; MAP kinase kinase kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity

Biological Process: negative regulation of JNK cascade; positive regulation of JNK activity; activation of MAPKK activity; protein amino acid autophosphorylation; mitotic cell cycle G2/M transition DNA damage checkpoint; MAPKKK cascade; positive regulation of JNK cascade; response to stress; DNA repair; response to DNA damage stimulus; phosphorylation; protein amino acid phosphorylation; positive regulation of stress-activated MAPK cascade

Similar Products

Product Notes

The Taok3 taok3 (Catalog #AAA642620) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TAOK3 (DPK, JIK, KDS, MAP3K18, Serine/Threonine-protein Kinase TAO3, Cutaneous T-cell Lymphoma-associated Antigen HD-CL-09, Dendritic Cell-derived Protein Kinase, JNK/SAPK-inhibitory Kinase, Jun Kinase-inhibitory Kinase, Kinase from Chicken Homolog A, Tho reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAOK3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the Taok3 taok3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LNAYQSKIKM QTEAQHEREL QKLEQRVSLR RAHLEQKIEE ELAALQKERS ERIKNLLERQ EREIETFDME SLRMGFGNLV TLDFPKEDYR. It is sometimes possible for the material contained within the vial of "TAOK3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.