Immunohistochemistry (IHC)
(Anti-SP140 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human SP140 Monoclonal Antibody | anti-SP140 antibody
Mouse Monoclonal [clone 3F9] (IgG2a,k) to Human SP140
Gene Names
SP140; LYSP100; LYSP100-A; LYSP100-B
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Protein A Purified
Synonyms
SP140; Monoclonal Antibody; Mouse Monoclonal [clone 3F9] (IgG2a; k) to Human SP140; Anti-SP140 Antibody (clone 3F9) IHC-plus; Nuclear autoantigen Sp-140; Speckled 140 kDa; LYSP100; SP140 nuclear body protein; LYSP100-A; LYSP100-B; Nuclear body protein SP140; Human SP140; anti-SP140 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3F9
Specificity
Human SP140
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
867
Applicable Applications for anti-SP140 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml)
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections.
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections.
Target Species
Human
Immunogen Description
SP140 (NP_009168, 504 a.a. ~ 613 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
SP140 antibody was raised against sP140 (NP_009168, 504 a.a. ~ 613 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Immunohistochemistry (IHC)
(Anti-SP140 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-SP140 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-SP140 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-SP140 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
91,673 Da
NCBI Official Full Name
nuclear body protein SP140 isoform 1
NCBI Official Synonym Full Names
SP140 nuclear body protein
NCBI Official Symbol
SP140
NCBI Official Synonym Symbols
LYSP100; LYSP100-A; LYSP100-B
NCBI Protein Information
nuclear body protein SP140; speckled 140 kDa; nuclear autoantigen Sp-140; lymphoid-specific SP100 homolog; lymphoid-restricted homolog of Sp100
UniProt Protein Name
Nuclear body protein SP140
Protein Family
UniProt Gene Name
SP140
UniProt Entry Name
SP140_HUMAN
Uniprot Description
SP140: Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: nucleoplasm; PML body; cytoplasm; nuclear envelope; nucleus
Molecular Function: protein binding; DNA binding; zinc ion binding; chromatin binding; transcription factor activity
Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent; defense response
Research Articles on SP140
Similar Products
Product Notes
The SP140 sp140 (Catalog #AAA246438) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 3F9] (IgG2a,k) to Human SP140 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SP140 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA, IHC-P (5 ug/ml) Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Researchers should empirically determine the suitability of the SP140 sp140 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SP140, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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