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Immunohistochemistry (IHC) (Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE))

Mouse anti-Human PPIC / Cyclophilin C Monoclonal Antibody | anti-PPIC antibody

Mouse Monoclonal [clone AT3C6] (IgG2b,k) to Human PPIC / Cyclophilin C

Gene Names
PPIC; CYPC
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Protein G Purified
Synonyms
PPIC / Cyclophilin C; Monoclonal Antibody; Mouse Monoclonal [clone AT3C6] (IgG2b; k) to Human PPIC / Cyclophilin C; Anti-PPIC / Cyclophilin C Antibody (clone AT3C6) IHC-plus; Cyclophilin C; CYPC; Parvulin; PPIase C; Rotamase C; Human PPIC; anti-PPIC antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
AT3C6
Specificity
Human PPIC / Cyclophilin C
Purity/Purification
Protein G Purified
Form/Format
PBS, pH 7.4, 0.1% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
212
Applicable Applications for anti-PPIC antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (10 ug/ml), WB (1:1000)
Target Species
Human
Immunogen Description
Recombinant human PPIC (39-197aa) protein purified from E Coli.
Immunogen Type
Recombinant protein
Immunogen
PPIC / Cyclophilin C antibody was raised against recombinant human PPIC (39-197aa) protein purified from E Coli.
Preparation and Storage
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

Immunohistochemistry (IHC)

(Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western Blot: The HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PPIC antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.)

Western Blot (WB) (Western Blot: The HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PPIC antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,763 Da
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase C
NCBI Official Synonym Full Names
peptidylprolyl isomerase C (cyclophilin C)
NCBI Official Symbol
PPIC
NCBI Official Synonym Symbols
CYPC
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase C; PPIase C; parvulin; rotamase C; cyclophilin C
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase C
UniProt Gene Name
PPIC
UniProt Synonym Gene Names
CYPC; PPIase C
UniProt Entry Name
PPIC_HUMAN

NCBI Description

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

Uniprot Description

PPIC: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family.

Protein type: Cyclophilin; EC 5.2.1.8; Isomerase

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: cytoplasm

Molecular Function: peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding

Biological Process: protein peptidyl-prolyl isomerization; protein folding

Research Articles on PPIC

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Product Notes

The PPIC ppic (Catalog #AAA249053) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone AT3C6] (IgG2b,k) to Human PPIC / Cyclophilin C reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPIC / Cyclophilin C can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (10 ug/ml), WB (1:1000). Researchers should empirically determine the suitability of the PPIC ppic for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPIC / Cyclophilin C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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